Pancreatic tumors are highly desmoplastic and immunosuppressive. Delivery and
distribution of drugs within pancreatic tumors are compromised due to intrinsic physical and …

Angiogenesis plays a critical role within the human body, from the early stages of life (ie,
embryonic development) to life-threatening diseases (eg, cancer, heart attack, stroke, wound …

Nature represents a rich source of compounds used for the treatment of many diseases.
Camptothecin (CPT), isolated from the bark of Camptotheca acuminata, is a cytotoxic …

The regeneration of articular cartilage remains a great challenge due to the difficulty in
effectively enhancing spontaneous healing. Recently, the combination of implanted stem …

Although nanomedicine has been highly investigated for cancer treatment over the past
decades, only a few nanomedicines are currently approved and in the market; making this …

A pivotal cause of death in the modern world, cancer is an insidious pathology that should
be diagnosed at an early stage for successful treatment. Development of therapeutic …

Polyphosphoesters (PPEs) are a class of (bio) degradable polymers with high chemical
versatility and functionality. In particular, water-soluble PPEs with the phosphoester group in …

Lung cancer is the leading cause of cancer‐related mortality both in men and women and
accounts for 18.4% of all cancer‐related deaths. Although advanced therapy methods have …

Modifying biological agents with polymers such as polyethylene glycol (PEG) has
demonstrated clinical benefits; however, post-market surveillance of PEGylated derivatives …

Colorectal cancer (CRC) is a heterogeneous disease with high incidence and mortality
worldwide. The efficacy of conventional CRC chemotherapy is hampered by poor drug …