Radiochemistry for positron emission tomography

J Rong, A Haider, TE Jeppesen, L Josephson… - Nature …, 2023 - nature.com
Positron emission tomography (PET) constitutes a functional imaging technique that is
harnessed to probe biological processes in vivo. PET imaging has been used to diagnose …

Chemistry for Positron Emission Tomography: Recent Advances in 11C‐, 18F‐, 13N‐, and 15O‐Labeling Reactions

X Deng, J Rong, L Wang, N Vasdev… - Angewandte Chemie …, 2019 - Wiley Online Library
Positron emission tomography (PET) is a molecular imaging technology that provides
quantitative information about function and metabolism in biological processes in vivo for …

Fast carbon isotope exchange of carboxylic acids enabled by organic photoredox catalysis

D Kong, M Munch, Q Qiqige, CJC Cooze… - Journal of the …, 2021 - ACS Publications
Carbazole/cyanobenzene photocatalysts promote the direct isotopic carboxylate exchange
of C (sp3) acids with labeled CO2. Substrates that are not compatible with transition-metal …

Arginase as a potential biomarker of disease progression: a molecular imaging perspective

G S. Clemente, A van Waarde, I F. Antunes… - International Journal of …, 2020 - mdpi.com
Arginase is a widely known enzyme of the urea cycle that catalyzes the hydrolysis of L-
arginine to L-ornithine and urea. The action of arginase goes beyond the boundaries of …

Modern strategies for carbon isotope exchange

A Labiche, A Malandain, M Molins… - Angewandte Chemie …, 2023 - Wiley Online Library
In contrast to stable and natural abundant carbon‐12, the synthesis of organic molecules
with carbon (radio) isotopes must be conceived and optimized in order to navigate through …

Carbon Dioxide Radical Anion by Photoinduced Equilibration between Formate Salts and [11C, 13C, 14C]CO2: Application to Carbon Isotope Radiolabeling

A Malandain, M Molins, A Hauwelle… - Journal of the …, 2023 - ACS Publications
The need for carbon-labeled radiotracers is increasingly higher in drug discovery and
development (carbon-14, β–, t 1/2= 5730 years) as well as in positron emission tomography …

New methodologies for the preparation of carbon-11 labeled radiopharmaceuticals

K Dahl, C Halldin, M Schou - Clinical and Translational Imaging, 2017 - Springer
Purpose This short review aims to cover the more recent and promising developments of
carbon-11 (11 C) labeling radiochemistry and its utility in the production of novel …

Development and application of several fluorescent probes in near infrared region

Y Wang, H Yu, Y Zhang, C Jia, M Ji - Dyes and Pigments, 2021 - Elsevier
Life in the body depends on the regulation of various substances, including metal ions,
anions, enzymes, thiols, ROS/RNS and so on. Fluorescent probe can be used for …

Transition‐metal‐free carbon isotope exchange of phenyl acetic acids

G Destro, K Horkka, O Loreau, DA Buisson… - Angewandte …, 2020 - Wiley Online Library
A transition‐metal‐free carbon isotope exchange procedure on phenyl acetic acids is
described. Utilizing the universal precursor CO2, this protocol allows the carbon isotope to …

Palladium-catalyzed molybdenum hexacarbonyl-mediated gas-free carbonylative reactions

L Åkerbladh, LR Odell, M Larhed - Synlett, 2019 - thieme-connect.com
This account summarizes Pd (0)-catalyzed Mo (CO) 6-mediated gas-free carbonylative
reactions published in the period October 2011 to May 2018. Presented reactions include …