The population and reactivity of two low-lying excited states in [Ru (bpy) 2 (dppn)] 2+(bpy= 2,
2′-bipyridine, dppn= benzo [i] dipyrido [3, 2-a: 2′, 3′-c] phenazine), a weakly emissive …

DNA intercalation by threading is expected to yield high affinity and slow dissociation,
properties desirable for DNA-targeted therapeutics. To measure these properties, we utilize …

Threading intercalation is an unusual DNA binding mode with significantly slower
association and dissociation rates compared with classical intercalation. The latter has been …

The quenching of the 3MLCT emission of three Ru (II) complexes of known DNA binding
mode is compared. This work shows that relative binding constants dictate whether …

The interactions of the naturally available botanicals with DNA molecules have received
considerable attention owing to the potential to develop for medicinal agents. In this study …

The slow dissociation of DNA threading intercalators makes them interesting as model
compounds in the search for new DNA targeting drugs, as there appears to be a correlation …

Threading intercalation is an unusual DNA binding mode that displays extremely slow
dissociation kinetics, which is an important feature for cytotoxicity, making threading …

Staphylococcus aureus is a Gram-positive bacterium that causes 320,000 infections
annually and is associated with diseases such as sepsis, endocarditis, and necrotizing …

In vitro DNA–drug interaction studies can give information that is important both for
therapeutic and diagnostic purposes, such as DNA sequence selectivity and binding …

Ever since the discovery of the role of DNA as the template for protein synthesis, efforts have
been made to develop DNA targeted drugs. One of the major challenges in the design of …