Advances in PET imaging of cancer

J Schwenck, D Sonanini, JM Cotton… - Nature Reviews …, 2023 - nature.com
Molecular imaging has experienced enormous advancements in the areas of imaging
technology, imaging probe and contrast development, and data quality, as well as machine …

Imaging hypoxia to improve radiotherapy outcome

MR Horsman, LS Mortensen, JB Petersen… - Nature reviews Clinical …, 2012 - nature.com
Reduced oxygen levels (hypoxia) is one of the most important factors influencing clinical
outcome after radiotherapy. This is primarily because hypoxic cells are resistant to radiation …

The clinical importance of assessing tumor hypoxia: relationship of tumor hypoxia to prognosis and therapeutic opportunities

C WalshJoseph, C KolbHartmuth - Antioxidants & redox signaling, 2014 - liebertpub.com
Tumor hypoxia is a well-established biological phenomenon that affects the curability of
solid tumors, regardless of treatment modality. Especially for head and neck cancer patients …

Imaging tumour hypoxia with positron emission tomography

IN Fleming, R Manavaki, PJ Blower, C West… - British journal of …, 2015 - nature.com
Hypoxia, a hallmark of most solid tumours, is a negative prognostic factor due to its
association with an aggressive tumour phenotype and therapeutic resistance. Given its …

Targeting hypoxia to improve non–small cell lung cancer outcome

A Salem, MC Asselin, B Reymen… - JNCI: Journal of the …, 2018 - academic.oup.com
Oxygen deprivation (hypoxia) in non–small cell lung cancer (NSCLC) is an important factor
in treatment resistance and poor survival. Hypoxia is an attractive therapeutic target …

Whole-body diffusion-weighted MR imaging in cancer: current status and research directions

AR Padhani, DM Koh, DJ Collins - Radiology, 2011 - pubs.rsna.org
Diffusion-weighted (DW) magnetic resonance (MR) imaging is emerging as a powerful
clinical tool for directing the care of patients with cancer. Whole-body DW imaging is almost …

[HTML][HTML] Exploratory prospective trial of hypoxia-specific PET imaging during radiochemotherapy in patients with locally advanced head-and-neck cancer

D Zips, K Zöphel, N Abolmaali, R Perrin… - Radiotherapy and …, 2012 - Elsevier
PURPOSE: To explore in a prospective trial the prognostic value of hypoxia imaging before
and during radiochemotherapy in patients with locally advanced head and neck cancer …

Molecular imaging–based dose painting: A novel paradigm for radiation therapy prescription

SM Bentzen, V Gregoire - Seminars in radiation oncology, 2011 - Elsevier
Dose painting is the prescription of a nonuniform radiation dose distribution to the target
volume based on functional or molecular images shown to indicate the local risk of relapse …

Advances in radiotherapy for head and neck cancer

V Grégoire, JA Langendijk, S Nuyts - Journal of Clinical Oncology, 2015 - ascopubs.org
Over the last few decades, significant improvements have been made in the radiotherapy
(RT) treatment of head and neck malignancies. The progressive introduction of intensity …

Magnetic resonance‐guided radiation therapy: a review

S Chin, CL Eccles, A McWilliam… - Journal of medical …, 2020 - Wiley Online Library
Magnetic resonance‐guided radiation therapy (MRgRT) is a promising approach to
improving clinical outcomes for patients treated with radiation therapy. The roles of image …