2, 2, 2-Trifluorodiazoethane (CF3CHN2) has been proven to be a valuable reagent for the
rapid synthesis of various classes of trifluoromethyl-substituted organic molecules in both …

Triazoles are important heterocyclic motifs that are widely found in molecular architectures
with medicinal and pharmaceutical properties. Considering the importance of these …

A visible-light-promoted three component reaction of diazo compounds, nitriles, and
carboxylic acids is reported. The reaction utilizes acceptor-only diazo compounds as …

A visible light-promoted generation of nitrilium ions from diazoacetates and nitriles has been
developed. The reaction utilized visible light transformation of diazoacetates to the free …

A base-mediated (3+ 2) cycloaddition of trifluoroacetohydrazonoyl chlorides with imidates
for the construction of 3-trifluoromethyl-1, 2, 4-triazoles has been described. This reaction is …

A Ru-catalyzed reaction of difluoroalkyl diazo compounds with Hantzsch ester under visible
light to achieve the formation of α-fluorovinylphosphonates via a radical process has been …

Here we report a strategy for the facile assembly of fused 3-trifluoromethyl-1, 2, 4-triazoles,
which are difficult to synthesize using traditional strategies, in 50–96% yields through a …

Herein, we describe a [2+ 1] annulation reaction of di/trifluorodiazoethane with (alkylidene)
malononitriles. This protocol offers a streamlined synthesis of a wide range of stereospecific …

Herein, a facile and straightforward route to synthesize 3-trifluoromethyl-1, 2, 4-triazoles via
copper-mediated [3+ 2] cycloaddition of trifluoroacetimidoyl chlorides and N …

A [3+ 2] cycloaddition reaction of unstable difluoromethylphosphonate-containing
diazoalkanes with vinyl sulfones under simple reaction conditions is developed, which …