[HTML][HTML] Host factors facilitating SARS‐CoV‐2 virus infection and replication in the lungs

S Boutin, D Hildebrand, S Boulant, M Kreuter… - Cellular and Molecular …, 2021 - Springer
SARS-CoV-2 is the virus causing the major pandemic facing the world today. Although,
SARS-CoV-2 primarily causes lung infection, a variety of symptoms have proven a systemic …

[HTML][HTML] New science, drug regulation, and emergent public health issues: The work of FDA's division of applied regulatory science

K Chiu, R Racz, K Burkhart, J Florian, K Ford… - Frontiers in …, 2023 - frontiersin.org
The US Food and Drug Administration (FDA) Division of Applied Regulatory Science
(DARS) moves new science into the drug review process and addresses emergent …

[HTML][HTML] Early life exposure of infants to benzylpenicillin and gentamicin is associated with a persistent amplification of the gut resistome

DV Patangia, G Grimaud, CA O'Shea, CA Ryan… - Microbiome, 2024 - Springer
Background Infant gut microbiota is highly malleable, but the long-term longitudinal impact
of antibiotic exposure in early life, together with the mode of delivery on infant gut microbiota …

[HTML][HTML] Acinetobacter calcoaceticus is Well Adapted to Withstand Intestinal Stressors and Modulate the Gut Epithelium

JS Glover, BD Browning, TD Ticer, AC Engevik… - Frontiers in …, 2022 - frontiersin.org
Background: The gastrointestinal tract has been speculated to serve as a reservoir for
Acinetobacter, however little is known about the ecological fitness of Acinetobacter strains in …

Alpha-terpineol grafted acetylated lentinan as an anti-bacterial adhesion agent

Q Ding, T Zhuang, P Fu, Q Zhou, L Luo, Z Dong… - Carbohydrate …, 2022 - Elsevier
Biomedical implants-associated bacterial infections have become a major threat to human
health. Therefore, it is meaningful to develop new antibacterial strategies to solve this …

[HTML][HTML] The microbiome in post-acute infection syndrome (PAIS)

C Guo, B Yi, J Wu, J Lu - Computational and Structural Biotechnology …, 2023 - Elsevier
ABSTRACT Post-Acute Infection Syndrome (PAIS) is a relatively new medical terminology
that represents prolonged sequelae symptoms after acute infection by numerous pathogenic …

In Vitro Models for Investigating Intestinal Host–Pathogen Interactions

R McCoy, S Oldroyd, W Yang, K Wang… - Advanced …, 2024 - Wiley Online Library
Infectious diseases are increasingly recognized as a major threat worldwide due to the rise
of antimicrobial resistance and the emergence of novel pathogens. In vitro models that can …

Antibiotic changes host susceptibility to Eimeria falciformis infection associated with alteration of gut microbiota

Y Gong, X Liu, S Zhang, X Tang, J Zou… - Infection and …, 2022 - Am Soc Microbiol
Eimeria falciformis is a murine-infecting coccidium that mainly infects the cecum and colon
where it coexists with a large number of endogenous bacteria. Here, we found that mice …

[HTML][HTML] Bioengineered probiotics: synthetic biology can provide live cell therapeutics for the treatment of foodborne diseases

KCP Cruz, LO Enekegho, DT Stuart - Frontiers in Bioengineering and …, 2022 - frontiersin.org
The rising prevalence of antibiotic resistant microbial pathogens presents an ominous health
and economic challenge to modern society. The discovery and large-scale development of …

[HTML][HTML] The gut microbiota: master of puppets connecting the epidemiology of infectious, autoimmune, and metabolic disease

OFA Larsen, M van der Grint, C Wiegers… - Frontiers in …, 2022 - frontiersin.org
Infectious, autoimmune, and metabolic diseases put an enormous pressure on both quality
of life and the economy. For all three disease types, it is known that the quality of the gut …