Association between BRAF (V600E) mutation and clinicopathological features of papillary thyroid carcinoma: a Brazilian single-centre case series

D Pessôa-Pereira, MFS Medeiros, VMS Lima… - … of Endocrinology and …, 2019 - SciELO Brasil
Objectives: We aimed to investigate the prevalence of the BRAF (V600E) mutation in
consecutive cases of papillary thyroid carcinoma (PTC) in patients diagnosed and treated at …

Analysis of cuproptosis-related genes in Ulcerative colitis and immunological characterization based on machine learning

Z Wang, Y Wang, J Yan, Y Wei, Y Zhang… - Frontiers in …, 2023 - frontiersin.org
Cuproptosis is a novel form of cell death, mediated by protein lipid acylation and highly
associated with mitochondrial metabolism, which is regulated in the cell. Ulcerative colitis …

Revised criteria for diagnosis of NIFTP reveals a better correlation with tumor biological behavior

AC de Jesus Paniza, TB Mendes… - Endocrine …, 2019 - ec.bioscientifica.com
The recent reclassification of a follicular variant of papillary thyroid carcinoma (FVPTC)
subset as noninvasive follicular thyroid neoplasm with papillary-like nuclear features …

LIM domain-containing 2 (LIMD2) promotes the progress of ovarian cancer via the focal adhesion signaling pathway

L Chen, J Qian, Q You, J Ma - Bioengineered, 2021 - Taylor & Francis
Ovarian cancer (OC) is the leading cause of death from gynecological cancer. In this study,
we aimed to explore the role and potential mechanism of LIMD2 during the progression of …

LIMD2 regulates key steps of metastasis cascade in papillary thyroid cancer cells via MAPK crosstalk

RP Araldi, TC de Melo, D Levy, DM de Souza… - Cells, 2020 - mdpi.com
Although papillary thyroid carcinoma (PTC) has a good prognosis, 20–90% of patients show
metastasis to regional lymph nodes and 10–15% of patients show metastasis to distant sites …

LIMD2 targeted by miR‑34a promotes the proliferation and invasion of non‑small cell lung cancer cells

F Wang, Z Li, L Xu, Y Li, Y Li… - Molecular …, 2018 - spandidos-publications.com
A previous study indicated that LIM domain containing 2 (LIMD2) is an oncogene in a variety
of human cancers, including breast, bladder and thyroid cancers, and melanoma; however …

LIMD2 is a Prognostic and Predictive Marker in Patients With Esophageal Cancer Based on a ceRNA Network Analysis

Y Chen, X Huang, K Zhu, C Li, H Peng, L Chen… - Frontiers in …, 2021 - frontiersin.org
Globally, esophageal cancer (ECA) is the seventh most common cancer and sixth most
common cause of cancer-associated mortality. However, there are no reliable prognostic …

Machine learning algorithm improved automated droplet classification of ddPCR for detection of BRAF V600E in paraffin-embedded samples

GA Colozza-Gama, F Callegari, N Bešič, ACJ Paniza… - Scientific Reports, 2021 - nature.com
Somatic mutations in cancer driver genes can help diagnosis, prognosis and treatment
decisions. Formalin-fixed paraffin-embedded (FFPE) specimen is the main source of DNA …

LIMD2 promotes tumor proliferation, invasion, and epithelial-mesenchymal transition in clear cell renal cell carcinoma.

QY Zhong, XIE Ying-Wei, C Zhi-Liang… - …, 2022 - search.ebscohost.com
LIMD2 was found upregulated in various tumors and metastatic samples and associated
with a poor prognosis. But the role of LIMD2 in clear cell renal cell carcinoma (ccRCC) …

Knockdown of LIMD2 inhibits the progression of ovarian carcinoma through ERK1/2 pathway

H Hu, Y Wang, Y Dong, L Wang, Y Chen, Y Zhou… - Molecular Biology …, 2023 - Springer
Background The incidence rate of ovarian carcinoma (OC) is the third of the female
reproductive system malignant tumors, while its mortality rate ranks first among causes of …