Restless legs syndrome

M Manconi, D Garcia-Borreguero… - Nature reviews Disease …, 2021 - nature.com
Restless legs syndrome (RLS) is a common sensorimotor disorder characterized by an urge
to move that appears during rest or is exacerbated by rest, that occurs in the evening or night …

The management of restless legs syndrome: an updated algorithm

MH Silber, MJ Buchfuhrer, CJ Earley, BB Koo… - Mayo Clinic …, 2021 - Elsevier
Restless legs syndrome (RLS) is a common disorder. The population prevalence is 1.5% to
2.7% in a subgroup of patients having more severe RLS with symptoms occurring 2 or more …

Comorbidities, treatment, and pathophysiology in restless legs syndrome

C Trenkwalder, R Allen, B Högl, S Clemens… - The Lancet …, 2018 - thelancet.com
Restless legs syndrome, also known as Willis-Ekbom disease, is a common neurological
condition whose manifestation is affected by complex environmental and genetic …

[HTML][HTML] Restless legs syndrome: contemporary diagnosis and treatment

TR Gossard, LM Trotti, A Videnovic, EK St Louis - Neurotherapeutics, 2021 - Elsevier
Restless legs syndrome (RLS) is characterized by an uncomfortable urge to move the legs
while at rest, relief upon movement or getting up to walk, and worsened symptom severity at …

[HTML][HTML] Guidelines for the first-line treatment of restless legs syndrome/Willis–Ekbom disease, prevention and treatment of dopaminergic augmentation: a combined …

D Garcia-Borreguero, MH Silber, JW Winkelman… - Sleep medicine, 2016 - Elsevier
A Task Force was established by the International Restless Legs Syndrome Study Group
(IRLSSG) in conjunction with the European Restless Legs Syndrome Study Group …

Altered brain iron homeostasis and dopaminergic function in restless legs syndrome (Willis–Ekbom disease)

CJ Earley, J Connor, D Garcia-Borreguero, P Jenner… - Sleep medicine, 2014 - Elsevier
Restless legs syndrome (RLS), also known as Willis–Ekbom Disease (WED), is a
sensorimotor disorder for which the exact pathophysiology remains unclear. Brain iron …

Treatment of restless legs syndrome: Evidence‐based review and implications for clinical practice (Revised 2017)§

J Winkelmann, RP Allen, B Högl, Y Inoue… - Movement …, 2018 - Wiley Online Library
The objective of the current review was to update the previous evidence‐based medicine
review of treatments for restless legs syndrome published in 2008. All randomized …

Restless legs syndrome: from pathophysiology to clinical diagnosis and management

S Guo, J Huang, H Jiang, C Han, J Li, X Xu… - Frontiers in aging …, 2017 - frontiersin.org
Restless legs syndrome (RLS), a common neurological sensorimotor disorder in western
countries, has gained more and more attention in Asian countries. The prevalence of RLS is …

The restless legs syndrome

C Trenkwalder, W Paulus, AS Walters - The lancet neurology, 2005 - thelancet.com
The restless legs syndrome is a common disorder that encompasses an idiopathic form of
genetic or unknown origin and symptomatic forms associated with many causes …

[HTML][HTML] Sleep issues in Parkinson's disease and their management

JRP Zuzuárregui, EH During - Neurotherapeutics, 2020 - Elsevier
Parkinson's disease (PD) is an alpha-synucleinopathy that leads to prominent motor
symptoms including tremor, bradykinesia, and postural instability. Nonmotor symptoms …