Out for a RiPP: challenges and advances in genome mining of ribosomal peptides from fungi
SC Kessler, YH Chooi - Natural Product Reports, 2022 - pubs.rsc.org
Covering up to June 2021 Ribosomally synthesized and post-translationally modified
peptides (RiPPs) from fungi are an underexplored class of natural products, despite their …
peptides (RiPPs) from fungi are an underexplored class of natural products, despite their …
Mushroom toxins: chemistry and toxicology
X Yin, AA Yang, JM Gao - Journal of agricultural and food …, 2019 - ACS Publications
Mushroom consumption is a global tradition that is still gaining popularity. However, foraging
for wild mushrooms and accidental ingestion of toxic mushrooms can result in serious illness …
for wild mushrooms and accidental ingestion of toxic mushrooms can result in serious illness …
Comparative Mitogenome Analysis Reveals Mitochondrial Genome Differentiation in Ectomycorrhizal and Asymbiotic Amanita Species
Q Li, X He, Y Ren, C Xiong, X Jin, L Peng… - Frontiers in …, 2020 - frontiersin.org
In this present study, we assembled and analyzed the mitogenomes of two asymbiotic and
six ectomycorrhizal Amanita species based on next-generation sequencing data. The size of …
six ectomycorrhizal Amanita species based on next-generation sequencing data. The size of …
Lateral flow immunoassay (LFIA) for the detection of lethal amatoxins from mushrooms
The mushroom poison that causes the most deaths is the class of toxins known as
amatoxins. Current methods to sensitively and selectively detect these toxins are limited by …
amatoxins. Current methods to sensitively and selectively detect these toxins are limited by …
Genes and evolutionary fates of the amanitin biosynthesis pathway in poisonous mushrooms
H Luo, HE Hallen-Adams, Y Lüli… - Proceedings of the …, 2022 - National Acad Sciences
The deadly toxin α-amanitin is a bicyclic octapeptide biosynthesized on ribosomes. A
phylogenetically disjunct group of mushrooms in Agaricales (Amanita, Lepiota, and …
phylogenetically disjunct group of mushrooms in Agaricales (Amanita, Lepiota, and …
Invasive Californian death caps develop mushrooms unisexually and bisexually
Canonical sexual reproduction among basidiomycete fungi involves the fusion of two
haploid individuals of different mating types, resulting in a heterokaryotic mycelial body …
haploid individuals of different mating types, resulting in a heterokaryotic mycelial body …
The Cyclic Peptide Toxins of Amanitaand Other Poisonous Mushrooms
J Walton - 2018 - Springer
Poisonous mushrooms have fascinated and horrified people for thousands of years.
Mushrooms in the large and charismatic genus Amanita in particular have featured in …
Mushrooms in the large and charismatic genus Amanita in particular have featured in …
Pangenomics of the death cap mushroom Amanita phalloides, and of Agaricales, reveals dynamic evolution of toxin genes in an invasive range
Abstract The poisonous European mushroom Amanita phalloides (the “death cap”) is
invading California. Whether the death caps' toxic secondary metabolites are evolving as it …
invading California. Whether the death caps' toxic secondary metabolites are evolving as it …
Discovery of novel fungal RiPP biosynthetic pathways and their application for the development of peptide therapeutics
E Vogt, M Künzler - Applied microbiology and biotechnology, 2019 - Springer
Bioactive peptide natural products are an important source of therapeutics. Prominent
examples are the antibiotic penicillin and the immunosuppressant cyclosporine which are …
examples are the antibiotic penicillin and the immunosuppressant cyclosporine which are …
Characterization of a dual function macrocyclase enables design and use of efficient macrocyclization substrates
Peptide macrocycles are promising therapeutic molecules because they are protease
resistant, structurally rigid, membrane permeable, and capable of modulating protein …
resistant, structurally rigid, membrane permeable, and capable of modulating protein …