Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

Approximately two decades have passed since the description of the first gene in the
Candida albicans ALS (agglutinin-like sequence) family. Since that time, much has been …

Highlights•Candidalysin is the first peptide toxin identified in any human fungal
pathogen.•Epithelial cells identify invasive C. albicans by detecting Candidalysin …

Despite the importance of fungal cell walls as the principle determinant of fungal
morphology and the defining element determining fungal interactions with other cells, few …

The ability of yeast cells to adhere to other cells or substrates is crucial for many yeasts. The
budding yeast Saccharomyces cerevisiae can switch from a unicellular lifestyle to a …

Flexible adaptation to the host environment is a critical trait that underpins the success of
numerous microbes. The polymorphic fungus Candida albicans has evolved to persist in the …

Background The co-existence of Candida albicans with the bacteria in the host tissues and
organs displays interactions at competitive, antagonistic, and synergistic levels. Several …

There has been extensive research on structure and function of fungal cell adhesion
molecules, but the most of the work has been about adhesins in Candida albicans and …

In the last twenty years, there has been a significant increase in invasive fungal infections,
which has corresponded with the expanding population of individuals with compromised …

One of defense mechanisms of the human immune system to counteract infection by the
opportunistic fungal pathogen Candida albicans is the recruitment of neutrophils to the site …