Diabetic retinopathy as the leading cause of blindness and early predictor of cascading complications—risks and mitigation

M Kropp, O Golubnitschaja, A Mazurakova… - Epma Journal, 2023 - Springer
Proliferative diabetic retinopathy (PDR) the sequel of diabetic retinopathy (DR), a frequent
complication of diabetes mellitus (DM), is the leading cause of blindness in the working-age …

[HTML][HTML] The diagnosis and treatment of glaucoma

AK Schuster, C Erb, EM Hoffmann… - Deutsches Ärzteblatt …, 2020 - ncbi.nlm.nih.gov
Background Glaucoma is a group of chronically progressive disorders of the optic nerve. In
this article, we present the epidemiology of and risk factors for glaucoma, as well as the …

Prevalence, incidence and future projection of diabetic eye disease in Europe: a systematic review and meta-analysis

JQ Li, T Welchowski, M Schmid, J Letow… - European journal of …, 2020 - Springer
To examine the prevalence and incidence of diabetic eye disease (DED) among individuals
with diabetes in Europe, a systematic review to identify all published European prevalence …

A systematic review of carotenoids in the management of age-related macular degeneration

DW Lem, PG Davey, DL Gierhart, RB Rosen - Antioxidants, 2021 - mdpi.com
Age-related macular degeneration (AMD) remains a leading cause of modifiable vision loss
in older adults. Chronic oxidative injury and compromised antioxidant defenses represent …

Deep ensemble learning for automated non-advanced AMD classification using optimized retinal layer segmentation and SD-OCT scans

M Moradi, Y Chen, X Du, JM Seddon - Computers in Biology and Medicine, 2023 - Elsevier
Background Accurate retinal layer segmentation in optical coherence tomography (OCT)
images is crucial for quantitatively analyzing age-related macular degeneration (AMD) and …

Nutrients for prevention of macular degeneration and eye-related diseases

HE Khoo, HS Ng, WS Yap, HJH Goh, HS Yim - Antioxidants, 2019 - mdpi.com
The risk of macular degeneration can be reduced through the consumption of antioxidant-
rich foods, supplements, and nutraceutical formulas. This review focuses on the …

Advances in development of exosomes for ophthalmic therapeutics

Y Tian, T Zhang, J Li, Y Tao - Advanced Drug Delivery Reviews, 2023 - Elsevier
Exosomes contain multiple bioactive molecules and maintain the connection between cells.
Recent advances in exosome-based therapeutics have witnessed unprecedented …

Roles of exosomes in ocular diseases

J Liu, F Jiang, Y Jiang, Y Wang, Z Li, X Shi… - International journal …, 2020 - Taylor & Francis
Exosomes, nanoscale vesicles with a diameter of 30 to 150 nm, are composed of a lipid
bilayer, protein, and genetic material. Exosomes are secreted by virtually all types of cells in …

Efficacy and safety of XEN®—Implantation vs. trabeculectomy: Data of a “real-world” setting

FM Wagner, AKG Schuster, J Emmerich… - PLoS …, 2020 - journals.plos.org
Objective To compare surgical success, postoperative intraocular pressure and complication
rates between trabeculectomy and XEN gelstent surgery in a cohort of glaucoma patients in …

A comprehensive study capturing vision loss burden in Pakistan (1990-2025): Findings from the Global Burden of Disease (GBD) 2017 study

B Hassan, R Ahmed, B Li, A Noor, Z Hassan - PloS one, 2019 - journals.plos.org
This study aims to provide estimates, trends and projections of vision loss burden in
Pakistan from 1990 to 2025. Global Burden of Diseases, Injuries, and Risk Factors Study …