Gout, a crystalline arthropathy caused by the deposition of monosodium urate crystals in the
articular and periarticular soft tissues, is a frequent cause of painful arthropathy. Imaging has …

Although diagnosing gout generally is straightforward, atypical disease may present a
challenge if it is associated with unusual symptoms or sites, discordant serum urate level, or …

Gout is a disorder that manifests as a spectrum of clinical and pathologic features built on a
foundation of an excess body burden of uric acid, manifested in part by hyperuricemia …

Objectives Determine the efficacy and safety of daily lesinurad (200 or 400 mg orally) added
to allopurinol in patients with serum uric acid (sUA) above target in a 12-month, randomised …

Purpose To estimate the accuracy, sensitivity, specificity, and interobserver agreement of
dual-energy computed tomography (CT) in detection of uric acid crystals in joints or …

Objective The primary objective of this prospective case-control study was to assess the
diagnostic value of several intra-articular and periarticular ultrasound (US)-detected …

Objective The authors prospectively determined:(1) the specificity and sensitivity of dual
energy CT (DECT) for gout; and (2) the interobserver and intraobserver reproducibility for …

The tophus is the cardinal feature of advanced gout. This review summarises recent
research into the biology, impact and treatment of tophaceous gout. Microscopically, tophi …

Gout is a major health problem in the United States; it affects 8.3 million people, which is
approximately 4% of the adult population. Gout is most often diagnosed and managed in …

Background Allopurinol, a xanthine oxidase inhibitor, is considered one of the most effective
urate‐lowering drugs and is frequently used in the treatment of chronic gout. Objectives To …