Both the initiation and the resolution of inflammatory responses are governed by the
sequential activation, migration, and control/suppression of immune cells at the site of injury …

Specialized pro-resolving mediators (SPMs) are endogenous small molecules produced
mainly from dietary omega-3 polyunsaturated fatty acids by both structural cells and cells of …

Background Resolution of inflammation is an active and regulated process that leads to the
clearance of cell debris and immune cells from the challenged tissue, facilitating the …

Inflammation and neuroinflammation are critical mechanisms in the generation of
neuropathic pain that is experienced in several chronic diseases. The aberrant inflammation …

After the initiation of inflammation, a series of processes start to resolve the inflammation. A
group of endogenous lipid mediators, namely specialized pro‐resolving lipid mediators is at …

Specialized pro-resolving mediators (SPMs) are lipid mediators derived from poly-
unsaturated fatty acids (PUFAs) which have been demonstrated to have an important role in …

Appropriate inflammation is an effective weapon for the body to fight against harmful stimuli,
while excessive or prolonged inflammatory reactions could lead to tissue destruction …

Arachidonic acid (AA) plays a critical role in inflammatory regulation and secondary injury
after spinal cord injury (SCI). However, the overall AA metabolism profile in the acute phase …

Lipoxins (LXs) are generated from arachidonic acid and are involved in the resolution of
inflammation and confer protection in a variety of pathological processes. In the nervous …

Lipids are organic compounds insoluble in water with a variety of metabolic and non-
metabolic functions. They not only represent an efficient energy substrate but can also act as …