Epithelial‐mesenchymal transition (EMT) is a complex process with a primordial role in
cellular transformation whereby an epithelial cell transforms and acquires a mesenchymal …

Triple-negative (TNBC) is the most lethal subtype of breast cancer owing to high
heterogeneity, aggressive nature, and lack of treatment options. Chemotherapy remains the …

Triple-negative breast cancer (TNBC) is not a unique disease, encompassing multiple
entities with marked histopathological, transcriptomic and genomic heterogeneity. Despite …

Triple negative breast cancers (TNBCs) are defined by the lack of estrogen receptor (ER),
progesterone receptor (PR), and human epidermal growth factor receptor 2 expression, and …

Triple-negative breast cancer (TNBC) is associated with high recurrence rates, high
incidence of distant metastases, and poor overall survival (OS). Taxane and anthracycline …

Cancer therapy exerts a strong selection pressure that shapes tumor evolution, yet our
knowledge of how tumors change during treatment is limited. Here, we report the analysis of …

Synthesis, deposition, and interactions of hyaluronan (HA) with its cellular receptor CD44
are crucial events that regulate the onset and progression of tumors. The intracellular …

Conventional anticancer therapies, such as chemo-and/or radio-therapy are often unable to
completely eradicate cancers due to abnormal tumor microenvironment, as well as …

Cancer stem cells are a progressive concept to account for the cell biological nature of
cancer. Despite the controversies regarding the cancer stem cell model, it has the potential …

Cancer stem cells (CSCs) represent a unique subpopulation of self-renewing oncogenic
cells that drive cancer initiation and progression. CSCs often acquire multidrug and …