Stabilization of proteins encapsulated in injectable poly (lactide-co-glycolide)

G Zhu, SR Mallery, SP Schwendeman - Nature biotechnology, 2000 - nature.com
Controlled release from biodegradable polymers is a novel approach to replace daily painful
injections of protein drugs. A major obstacle to development of these polymers is the need to …

Injectable glycosaminoglycan hydrogels for controlled release of human basic fibroblast growth factor

S Cai, Y Liu, XZ Shu, GD Prestwich - Biomaterials, 2005 - Elsevier
Synthetic hydrogel mimics of the extracellular matrix (ECM) were created by crosslinking a
thiol-modified analog of heparin with thiol-modified hyaluronan (HA) or chondroitin sulfate …

Active growth factor delivery from poly (D, L-lactide-co-glycolide) foams prepared in supercritical CO2

DD Hile, ML Amirpour, A Akgerman… - Journal of controlled …, 2000 - Elsevier
A method for the production of microporous poly (d, l-lactide-co-glycolide) foams containing
encapsulated proteins using supercritical carbon dioxide is described. Foams generated as …

Injectable biomaterials for delivery of interleukin-1 receptor antagonist: toward improving its therapeutic effect

AEB Clements, WL Murphy - Acta Biomaterialia, 2019 - Elsevier
Abstract Interleukin-1 receptor antagonist (IL-1Ra) is a naturally occurring anti-inflammatory
cytokine that inhibits IL-1 activity and has been proposed to treat a wide variety of systemic …

Induction of angiogenesis and neural progenitor cells by basic fibroblast growth factor‐releasing polyglycolic acid sheet following focal cerebral infarction in mice

Y Ito, A Oyane, M Yasunaga, K Hirata… - … Research Part A, 2022 - Wiley Online Library
Biodegradable sheets loaded with basic fibroblast growth factor (bFGF) are prepared as
novel bFGF‐releasing systems from polyglycolic acid nonwoven fabric by oxygen plasma …

[HTML][HTML] Microphthalmia, persistent hyperplastic hyaloid vasculature and lens anomalies following overexpression of VEGF-A188 from the αA-crystallin promoter

CS Rutland, CA Mitchell, M Nasir, MA Konerding… - Molecular …, 2007 - ncbi.nlm.nih.gov
Purpose During growth of the embryonic eye, dose-and site-specific expression of heparin-
binding growth factors is critical for the formation of an appropriate vascular supply …

Chondrocyte transplantation using PGLA/Polydioxanon fleeces

C Perka, O Schultz, M Sittinger, H Zippel - Der Orthopäde, 2000 - Springer
Zusammenfassung Die Transplantation von chondrogenen Zellen in supportiven
Trägerstrukturen erweist sich zunehmend als eine alternative Methode zur Behandlung von …

Solvent-free protein encapsulation within biodegradable polymer foams

DD Hile, MV Pishko - Drug delivery, 2004 - Taylor & Francis
Microporous poly (D, L-lactide-co-glycolide) matrices containing encapsulated proteins were
fabricated in a solvent-free manner. Microporous foam was generated by saturating a …

Unique vascular phenotypes following over-expression of individual VEGFA isoforms from the developing lens

CA Mitchell, CS Rutland, M Walker, M Nasir, AJE Foss… - Angiogenesis, 2006 - Springer
Formation of a correctly organised vasculature and subsequently embryonic survival is
critically dependent on the dosage and site-specific expression of VEGF. Murine VEGF …

Controlled release of basic fibroblast growth factor from a water-floatable polyethylene nonwoven fabric sheet for maintenance culture of iPSCs

A Oyane, H Araki, M Nakamura, Y Aiki, K Higuchi… - RSC …, 2020 - pubs.rsc.org
Basic fibroblast growth factor (bFGF) is an essential supplement for culture media to support
the proliferation of human pluripotent stem cells, while preserving their pluripotency …