Myricetin bioactive effects: Moving from preclinical evidence to potential clinical applications

Y Taheri, HAR Suleria, N Martins, O Sytar… - … medicine and therapies, 2020 - Springer
Several flavonoids have been recognized as nutraceuticals, and myricetin is a good
example. Myricetin is commonly found in plants and their antimicrobial and antioxidant …

[HTML][HTML] Flavonoid–membrane interactions: Involvement of flavonoid–metal complexes in raft signaling

YS Tarahovsky, YA Kim, EA Yagolnik… - Biochimica et Biophysica …, 2014 - Elsevier
Flavonoids are polyphenolic compounds produced by plants and delivered to the human
body through food. Although the epidemiological analyses of large human populations did …

Genetic variation and sickle cell disease severity: a systematic review and meta-analysis

JK Kirkham, JH Estepp, MJ Weiss… - JAMA Network …, 2023 - jamanetwork.com
Importance Sickle cell disease (SCD) is a monogenic disorder, yet clinical outcomes are
influenced by additional genetic factors. Despite decades of research, the genetics of SCD …

[HTML][HTML] The impact of xanthine oxidase (XO) on hemolytic diseases

HM Schmidt, EE Kelley, AC Straub - Redox Biology, 2019 - Elsevier
Hemolytic diseases are associated with elevated levels of circulating free heme that can
mediate endothelial dysfunction directly via redox reactions with biomolecules or indirectly …

GC-MS analysis, antimicrobial, antioxidant, antilipoxygenase and cytotoxic activities of Jacaranda mimosifolia methanol leaf extracts and fractions

R Naz, TH Roberts, A Bano, A Nosheen, H Yasmin… - PLoS …, 2020 - journals.plos.org
Jacaranda mimosifolia trees are grown in frost-free regions globally. The aim of this study
was to evaluate the methanol crude extract and various fractions of increasing polarity of J …

Myricetin: biological activity related to human health

KS Park, Y Chong, MK Kim - Applied Biological Chemistry, 2016 - Springer
Abstract Myricetin (3, 5, 7, 3′, 4′, 5′-hexahydroxyflavone) is one of the natural flavonols
from fruit, vegetable, tea, and medicinal plants. A great deal of attention has been paid to this …

Antioxidant, Antimicrobial and Cytotoxic Properties as Well as the Phenolic Content of the Extract from Hancornia speciosa Gomes

UP Santos, JF Campos, HFV Torquato… - PLoS …, 2016 - journals.plos.org
Hancornia speciosa Gomes (Apocynaceae) is a fruit tree, popularly known as mangabeira,
and it is widely distributed throughout Brazil. Several parts of the plant are used in folk …

Gum Arabic as novel anti-oxidant agent in sickle cell anemia, phase II trial

L Kaddam, I Fadl-Elmula, OA Eisawi, HA Abdelrazig… - BMC hematology, 2017 - Springer
Background Sickle cell anemia patients suffer from oxidative stress due to chronic
inflammation and self-oxidation of sickle hemoglobin (Hb S). Chronic oxidative stress …

The effect of antioxidants on the properties of red blood cells from patients with sickle cell anemia

H Al Balushi, A Hannemann, D Rees, J Brewin… - Frontiers in …, 2019 - frontiersin.org
Oxidative damage to red blood cells (RBCs) may contribute to pathogenesis of sickle cell
anemia. Reducing the deleterious effects of oxidants by exposing RBCs to a number of …

Target identification and intervention strategies against amebiasis

S Nagaraja, S Ankri - Drug Resistance Updates, 2019 - Elsevier
Entamoeba histolytica is the etiological agent of amebiasis, which is an endemic parasitic
disease in developing countries and is the cause of approximately 70,000 deaths annually …