Models of psychedelic drug action: modulation of cortical-subcortical circuits
Classic psychedelic drugs such as psilocybin and lysergic acid diethylamide (LSD) have
recaptured the imagination of both science and popular culture, and may have efficacy in …
recaptured the imagination of both science and popular culture, and may have efficacy in …
International Union of Basic and Clinical Pharmacology. CX. Classification of receptors for 5-hydroxytryptamine; pharmacology and function
HT receptors expressed throughout the human body are targets for established therapeutics
and various drugs in development. Their diversity of structure and function reflects the …
and various drugs in development. Their diversity of structure and function reflects the …
Psychedelics
DE Nichols, EL Barker - Pharmacological reviews, 2016 - Elsevier
Psychedelics (serotonergic hallucinogens) are powerful psychoactive substances that alter
perception and mood and affect numerous cognitive processes. They are generally …
perception and mood and affect numerous cognitive processes. They are generally …
Hallucinogens and Serotonin 5-HT2A Receptor-Mediated Signaling Pathways
JF López-Giménez, J González-Maeso - Behavioral neurobiology of …, 2018 - Springer
The neuropsychological effects of naturally occurring psychoactive chemicals have been
recognized for millennia. Hallucinogens, which include naturally occurring chemicals such …
recognized for millennia. Hallucinogens, which include naturally occurring chemicals such …
[HTML][HTML] Endocannabinoid-mediated control of synaptic transmission
M Kano, T Ohno-Shosaku… - Physiological …, 2009 - journals.physiology.org
The discovery of cannabinoid receptors and subsequent identification of their endogenous
ligands (endocannabinoids) in early 1990s have greatly accelerated research on …
ligands (endocannabinoids) in early 1990s have greatly accelerated research on …
A review of central 5-HT receptors and their function
NM Barnes, T Sharp - Neuropharmacology, 1999 - Elsevier
It is now nearly 5 years since the last of the currently recognised 5-HT receptors was
identified in terms of its cDNA sequence. Over this period, much effort has been directed …
identified in terms of its cDNA sequence. Over this period, much effort has been directed …
Hallucinogens
DE Nichols - Pharmacology & therapeutics, 2004 - Elsevier
Hallucinogens (psychedelics) are psychoactive substances that powerfully alter perception,
mood, and a host of cognitive processes. They are considered physiologically safe and do …
mood, and a host of cognitive processes. They are considered physiologically safe and do …
Serotonin modulation of cortical neurons and networks
The serotonergic pathways originating in the dorsal and median raphe nuclei (DR and MnR,
respectively) are critically involved in cortical function. Serotonin (5-HT), acting on …
respectively) are critically involved in cortical function. Serotonin (5-HT), acting on …
Serotonin receptors
DE Nichols, CD Nichols - Chemical reviews, 2008 - ACS Publications
Serotonin, 5-hydroxytryptamine (5-HT), is one of the class of monoamine neurontransmitters,
all of which have a chemical template comprised of a basic amino group separated from an …
all of which have a chemical template comprised of a basic amino group separated from an …
[HTML][HTML] Psilocybin acutely alters the functional connectivity of the claustrum with brain networks that support perception, memory, and attention
Psychedelic drugs, including the serotonin 2a (5-HT 2A) receptor partial agonist psilocybin,
are receiving renewed attention for their possible efficacy in treating a variety of …
are receiving renewed attention for their possible efficacy in treating a variety of …