Antimicrobial peptides are a vital component of the innate immune system of all eukaryotic
organisms and many of these peptides have potent antifungal activity. They have potential …

Plant defensins are small, cysteine-rich peptides that possess biological activity towards a
broad range of organisms. Their activity is primarily directed against fungi, but bactericidal …

The incidence of invasive fungal infections is increasing worldwide, resulting in more than
1.6 million deaths every year. Due to growing antifungal drug resistance and the limited …

Mycoses are accountable for millions of infections yearly worldwide. Invasive candidiasis is
the most usual, presenting a high morbidity and mortality. Candida albicans remains the …

Just over a million people died globally in 2019 due to antibiotic resistance caused by
ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella …

Defensins are small basic amphiphilic peptides (up to 5 kDa) that have been shown to be
important effector molecules of the innate immune system of animals, plants and fungi. In …

Plant defensins are cationic peptides that are ubiquitous within the plant kingdom and
belong to a large superfamily of antimicrobial peptides found in several organisms …

The emergence of pathogens resistant to conventional antibiotics and the growing interest in
developing alternative natural antimicrobial agents have prompted a search for plant …

Over the last years, antimicrobial peptides (AMPs) have been the focus of intense research
toward the finding of a viable alternative to current antifungal drugs. Defensins are one of the …

The antifungal plant defensin RsAFP2 isolated from radish interacts with fungal
glucosylceramides and induces apoptosis in Candida albicans. To further unravel the …