[HTML][HTML] IL-35 is a novel responsive anti-inflammatory cytokine—a new system of categorizing anti-inflammatory cytokines

X Li, J Mai, A Virtue, Y Yin, R Gong, X Sha… - PloS one, 2012 - journals.plos.org
It remains unknown whether newly identified anti-inflammatory/immunosuppressive cytokine
interleukin-35 (IL-35) is different from other anti-inflammatory cytokines such as IL-10 and …

Interleukin newcomers creating new numbers in rheumatology: IL-34 to IL-38

G Clavel, A Thiolat, MC Boissier - Joint bone spine, 2013 - Elsevier
The development of innovative technologies is steadily increasing the body of knowledge on
molecules involved in physiological functions. Thus, several interleukins (ILs) have been …

IL‐35: a potential therapeutic target for controlling hepatitis B virus infection

XG Xiang, Q Xie - Journal of digestive diseases, 2015 - Wiley Online Library
Interleukin (IL)‐35, a recently identified cytokine of the IL‐12 family, is a potent
immunosuppressive cytokine secreted by regulatory T (Treg) cells and the newly reported …

The possible role of the novel cytokines il‐35 and il‐37 in inflammatory bowel disease

Y Li, Y Wang, Y Liu, Y Wang, X Zuo… - Mediators of …, 2014 - Wiley Online Library
Interleukin‐(IL‐) 35 and IL‐37 are newly discovered immune‐suppressing cytokines. They
have been described in inflammatory diseases such as collagen‐induced arthritis and …

Roles of M1 and M2 macrophages in herpes simplex virus 1 infectivity

DH Lee, H Ghiasi - Journal of virology, 2017 - Am Soc Microbiol
Macrophages are the predominant infiltrate in the corneas of mice that have been ocularly
infected with herpes simplex virus 1 (HSV-1). However, very little is known about the relative …

Decreased interleukin 35 and CD4+ EBI3+ T cells in patients with active systemic lupus erythematosus

H Ouyang, Y Shi, Z Wang, S Feng, S Kong, Y Lu… - The American journal of …, 2014 - Elsevier
Abstract Background Interleukin 35 (IL-35) is likely to contribute to the development of
autoimmune diseases, as the Epstein-Barr virus-induced gene protein 3 (EBI3) is the …

Distinct subunit pairing criteria within the heterodimeric IL-12 cytokine family

LL Jones, V Chaturvedi, C Uyttenhove, J Van Snick… - Molecular …, 2012 - Elsevier
The heterodimeric IL-12 cytokine family is characterized by the sharing of three α (p19, p28,
p35) and two β (p40 and Ebi3) subunits, and includes IL-12 (p35/p40), IL-23 (p19/p40), IL …

Regulatory role of oligodendrocyte gap junctions in inflammatory demyelination

CP Papaneophytou, E Georgiou, C Karaiskos… - Glia, 2018 - Wiley Online Library
Gap junctions (GJs) coupling oligodendrocytes to astrocytes and to other oligodendrocytes
are formed mainly by connexin47 (Cx47) and a smaller portion by connexin32 (Cx32) …

[HTML][HTML] IL-27 limits central nervous system viral clearance by promoting IL-10 and enhances demyelination

MTP de Aquino, P Kapil, DR Hinton… - The Journal of …, 2014 - journals.aai.org
IL-27 is a pleiotropic member of the IL-6 and IL-12 cytokine family composed of the IL-27p28
and the EBV-induced gene 3. IL-27 and its receptor mRNA are both upregulated in the CNS …

Association between IL-35 and coronary arterial lesions in children with Kawasaki disease

Y Su, S Feng, L Luo, R Liu, Q Yi - Clinical and experimental medicine, 2019 - Springer
Kawasaki disease (KD) arises due to the acute inflammation and immune system
dysfunction. This study investigated the relationship between the serum level of IL-35 and …