Mechanisms underlying dorsolateral prefrontal cortex contributions to cognitive dysfunction in schizophrenia
Kraepelin, in his early descriptions of schizophrenia (SZ), characterized the illness as having
“an orchestra without a conductor.” Kraepelin further speculated that this “conductor” was …
“an orchestra without a conductor.” Kraepelin further speculated that this “conductor” was …
Immunoneuropsychiatry—novel perspectives on brain disorders
Immune processes have a vital role in CNS homeostasis, resilience and brain reserve. Our
cognitive and social abilities rely on a highly sensitive and fine-tuned equilibrium of immune …
cognitive and social abilities rely on a highly sensitive and fine-tuned equilibrium of immune …
[HTML][HTML] The potential mechanism of postoperative cognitive dysfunction in older people
X Lin, Y Chen, P Zhang, G Chen, Y Zhou, X Yu - Experimental gerontology, 2020 - Elsevier
Postoperative cognitive dysfunction (POCD) is a common disorder following surgery, which
seriously threatens the quality of patients' life, especially the older people. Accumulating …
seriously threatens the quality of patients' life, especially the older people. Accumulating …
The role of inflammation in the treatment of schizophrenia
Background: Inflammation plays a major role in the onset and maintenance of
schizophrenia. The objective of the present work was to synthetize in a narrative review the …
schizophrenia. The objective of the present work was to synthetize in a narrative review the …
Cytokines and C-reactive protein alterations with respect to cognitive impairment in schizophrenia and bipolar disorder: a systematic review
Background The aim of this article was to perform a systematic review of studies
investigating the association between peripheral levels of cytokines and C-reactive protein …
investigating the association between peripheral levels of cytokines and C-reactive protein …
Peripheral inflammatory and neurotrophic biomarkers of cognitive impairment in schizophrenia: a meta-analysis
E Bora - Psychological medicine, 2019 - cambridge.org
BackgroundSchizophrenia is associated with significant cognitive impairment. However, the
pathophysiological mechanisms underlying cognitive dysfunction in schizophrenia remain …
pathophysiological mechanisms underlying cognitive dysfunction in schizophrenia remain …
Post-stroke cognitive impairment: a review focusing on molecular biomarkers
X Zhang, X Bi - Journal of Molecular Neuroscience, 2020 - Springer
Post-stroke cognitive impairment (PSCI), as one of the major complications after stroke,
refers to a series of syndromes from mild cognitive impairment to dementia caused by stroke …
refers to a series of syndromes from mild cognitive impairment to dementia caused by stroke …
[HTML][HTML] Inflammatory subgroups of schizophrenia and their association with brain structure: A semi-supervised machine learning examination of heterogeneity
Objective Immune system dysfunction is hypothesised to contribute to structural brain
changes through aberrant synaptic pruning in schizophrenia. However, evidence is mixed …
changes through aberrant synaptic pruning in schizophrenia. However, evidence is mixed …
Increased peripheral inflammation in schizophrenia is associated with worse cognitive performance and related cortical thickness reductions
HF North, J Bruggemann, V Cropley… - European archives of …, 2021 - Springer
While the biological substrates of brain and behavioural changes in persons with
schizophrenia remain unclear, increasing evidence implicates that inflammation is involved …
schizophrenia remain unclear, increasing evidence implicates that inflammation is involved …
C-reactive protein: higher during acute psychotic episodes and related to cortical thickness in schizophrenia and healthy controls
I Jacomb, C Stanton, R Vasudevan, H Powell… - Frontiers in …, 2018 - frontiersin.org
There is increasing evidence for the role of inflammation in schizophrenia, yet the stability of
increased peripheral inflammation in acute psychosis and the degree to which peripheral …
increased peripheral inflammation in acute psychosis and the degree to which peripheral …