Kraepelin, in his early descriptions of schizophrenia (SZ), characterized the illness as having
“an orchestra without a conductor.” Kraepelin further speculated that this “conductor” was …

Immune processes have a vital role in CNS homeostasis, resilience and brain reserve. Our
cognitive and social abilities rely on a highly sensitive and fine-tuned equilibrium of immune …

Postoperative cognitive dysfunction (POCD) is a common disorder following surgery, which
seriously threatens the quality of patients' life, especially the older people. Accumulating …

Background: Inflammation plays a major role in the onset and maintenance of
schizophrenia. The objective of the present work was to synthetize in a narrative review the …

Background The aim of this article was to perform a systematic review of studies
investigating the association between peripheral levels of cytokines and C-reactive protein …

BackgroundSchizophrenia is associated with significant cognitive impairment. However, the
pathophysiological mechanisms underlying cognitive dysfunction in schizophrenia remain …

Post-stroke cognitive impairment (PSCI), as one of the major complications after stroke,
refers to a series of syndromes from mild cognitive impairment to dementia caused by stroke …

Objective Immune system dysfunction is hypothesised to contribute to structural brain
changes through aberrant synaptic pruning in schizophrenia. However, evidence is mixed …

While the biological substrates of brain and behavioural changes in persons with
schizophrenia remain unclear, increasing evidence implicates that inflammation is involved …

There is increasing evidence for the role of inflammation in schizophrenia, yet the stability of
increased peripheral inflammation in acute psychosis and the degree to which peripheral …