Chromium is a pervasive environmental contaminant that is of great importance because of
its toxicity. Hexavalent chromium is a classified group 1 carcinogen with multiple complex …

Carcinogenic metals, such as nickel, arsenic, and chromium, are widespread environmental
and occupational pollutants. Chronic exposure to these metals has been connected with …

Exposure of the airways epithelium to environmental insults, including cigarette smoke,
results in increased oxidative stress due to unbalance between oxidants and antioxidants in …

Inhalation of hexavalent chromium [Cr (VI)] is associated with increased lung cancer risk
among workers in several industries, most notably chromate production workers exposed to …

DNA methylation plays an intricate role in the regulation of gene expression and events that
compromise the integrity of the methylome may potentially contribute to disease …

The bioactivation of pro-toxicants is the biological process through which some chemicals
are metabolized into reactive metabolites. Therefore, in vitro toxicological evaluation should …

There is a great interest in a better knowledge of the health effects caused by nanomaterials
exposures and, in particular to those induced by titanium dioxide nanoparticles (nano-TiO2) …

Abstract Hexavalent chromium [Cr (VI)] is a well-known carcinogen that can cause several
types of cancer including lung cancer. NF-E2-related factor 2 (Nrf2), the redox sensitive …

The complex process of carcinogenesis begins with transformation of a single cell to favor
aberrant traits such as loss of contact inhibition and unregulated proliferation–features found …

Abstract BEAS‐2B, an immortalized, human lung epithelial cell line, has been used to model
pulmonary epithelial function for over 30 years. The BEAS‐2B phenotype can be modulated …