The discovery of immune checkpoint inhibitors (ICIs) has now been universally
acknowledged as a significant breakthrough in tumor therapy after the targeted treatment of …

Breast cancer (BC) is the main cause of cancer-related mortality among women globally.
Despite substantial advances in the identification and management of primary tumors …

NK cells contribute to protective antitumor immunity, but little is known about the functional
states of NK cells in human solid tumors. To address this issue, we performed single-cell …

Background CD161, encoded by killer cell lectin-like receptor B1 gene, is a newly reported
candidate inhibitor of tumour-infiltrating T cells. Antibody-mediated CD161 blockade …

Simple Summary The tumor microenvironment (TME) is a complicated network composed of
various cells, signaling molecules, and extra cellular matrix. TME plays a crucial role in triple …

Simple Summary Recent years marked the discovery and increased understanding of the
role immune checkpoints play in immunity against cancer. This has revolutionized cancer …

The success of immune checkpoint therapy in cancer has changed our way of thinking,
promoting the design of future cancer treatments that places the immune system at the …

In treatments of solid tumors, adoptive transfer of ex vivo expanded natural killer (NK) cells
has dawned as a new paradigm. Compared with cytotoxic T lymphocytes, NK cells take a …

Introduction Natural killer (NK) cells plays a pivotal role in the control of viral infections, and
their function depend on the balance between their activating and inhibitory receptors. The …

Natural killer (NK) cells play a pivotal role in the immune system, especially in the
recognition and clearance of cancer cells and infected cells. Their effector function is …