Osteal macrophages (OsteoMacs) are a special subtype of macrophage residing in bony
tissues. Interesting findings from basic research have pointed to their vast and substantial …

The regulatory role of the immune system in maintaining bone homeostasis and restoring its
functionality, when disturbed due to trauma or injury, has become evident in recent years …

The recognition and importance of immune cells during bone regeneration, including
around bone biomaterials, has led to the development of an entire field termed …

Collagen is one of the important components of collagen membranes as well as the
extracellular matrix (ECM). Most previous studies have focused on combining collagen …

Multipotent mesenchymal stem cells (MSC) are reported to be immunoprivileged as well as
immunosuppressive. Hence, they are ideal candidates for allogeneic transplantation to …

Osteoimmunological interactions are central to maintaining bone homeostasis and are key
mechanisms in bone pathology. Macrophages are highly adaptable cells with pleiotropic …

The aim of the present study was to elucidate the role of osteoblasts in bisphosphonates-
related osteonecrosis of the jaw (BRONJ). The specific objective was to evaluate the effect …

Osteomyelitis (OM) is an infectious disease of the bone predominantly caused by the
opportunistic bacterium Staphylococcus aureus (S. aureus). Typically established upon …

Background Contrary to the minimal criteria proposed by the International Society for Cell
and Gene Therapy for defining multipotent mesenchymal stromal cells (MSC), human …

Although the primary roles of osteoblasts are to synthesize the components of bone matrix
and to regulate the activity of bone resorbing osteoclasts, there is growing realization that …