Synthesis and biological activities of thio-avarol derivatives

B Pejin, C Iodice, G Tommonaro… - Journal of natural …, 2008 - ACS Publications
Eleven new thio-avarol derivatives (3− 13) were synthesized. Their antimicrobial, brine
shrimp lethality, and free-radical scavenging activities and acetylcholinesterase inhibition …

Avarol and avarone, two new anti-inflammatory agents of marine origin

ML Ferrándiz, MJ Sanz, G Bustos, M Payá… - European journal of …, 1994 - Elsevier
The anti-inflammatory activity of avarol and avarone, sesquiterpenoid derivatives from the
Mediterranean sponge Dysidea avara, was investigated. Both compounds potently inhibited …

Investigating the antiparasitic potential of the marine sesquiterpene avarone, its reduced form avarol, and the novel semisynthetic thiazinoquinone analogue …

C Imperatore, R Gimmelli, M Persico, M Casertano… - Marine Drugs, 2020 - mdpi.com
The chemical analysis of the sponge Dysidea avara afforded the known sesquiterpene
quinone avarone, along with its reduced form avarol. To further explore the role of the …

Marine sesquiterpene/quinones

RJ Capon - Studies in natural products chemistry, 1995 - Elsevier
Publisher Summary This chapter discusses marine sesquiterpene/quinones. Although
marine sesquiterpene/quinones have predominantly been isolated from sponges, several …

Bioactive marine prenylated quinones/quinols

S de Rosa, G Tommonaro - Studies in Natural Products Chemistry, 2012 - Elsevier
Prenylated hydroquinones and related metabolites have been isolated from marine
organisms with a terpenoid portion that ranges from one to nine isoprene units. Triprenyl …

Analgesic and anti-inflammatory activities of a fraction rich in oncocalyxone A isolated from Auxemma oncocalyx

MAD Ferreira, ODRH Nunes, JB Fontenele… - Phytomedicine, 2004 - Elsevier
In the present work we studied the antinociceptive and antiedematogenic effects of a
quinone fraction (QF) isolated from the heartwood of Auxemma oncocalyx Taub. The major …

Enantioselective total synthesis of avarol and avarone

T Ling, AX Xiang… - Angewandte Chemie …, 1999 - Wiley Online Library
Formation of the C11− C1′ bond through application of Barton's radical decarboxylation
and quinone addition is the cornerstone of a new convergent and concise synthesis of the …

Further in vitro evaluation of antimicrobial activity of the marine sesquiterpene hydroquinone avarol

B Pejin, C Iodice, G Tommonaro… - Current …, 2014 - ingentaconnect.com
This work extends in vitro screening of antimicrobial activity of the sesquiterpene
hydroquinone avarol, a main secondary metabolite of the Mediterranean sponge species …

GC-MS profile of antimicrobial and antioxidant fractions from Cordia rothii roots

K Khan, S Firdous, A Ahmad, N Fayyaz… - Pharmaceutical …, 2016 - Taylor & Francis
Context: An ethnobotanical survey of Cordia rothii Roem. & Schult.(Boraginaceae) reveals it
as a medicinal plant. Objective: Antimicrobial and antioxidant potential evaluation and …

Total synthesis and antibacterial activity of dysidavarone A

B Schmalzbauer, J Herrmann, R Müller… - Organic letters, 2013 - ACS Publications
A concise total synthesis of dysidavarone A possessing the new “dysidavarane” carbon
skeleton has been accomplished by a convergent strategy, involving a stereoselective …