Quantitative phase imaging: recent advances and expanding potential in biomedicine
TL Nguyen, S Pradeep, RL Judson-Torres, J Reed… - ACS …, 2022 - ACS Publications
Quantitative phase imaging (QPI) is a label-free, wide-field microscopy approach with
significant opportunities for biomedical applications. QPI uses the natural phase shift of light …
significant opportunities for biomedical applications. QPI uses the natural phase shift of light …
Liquid–liquid phase separation in tumor biology
X Tong, R Tang, J Xu, W Wang, Y Zhao, X Yu… - Signal Transduction and …, 2022 - nature.com
Liquid–liquid phase separation (LLPS) is a novel principle for explaining the precise spatial
and temporal regulation in living cells. LLPS compartmentalizes proteins and nucleic acids …
and temporal regulation in living cells. LLPS compartmentalizes proteins and nucleic acids …
Slow TCA flux and ATP production in primary solid tumours but not metastases
Tissues derive ATP from two pathways—glycolysis and the tricarboxylic acid (TCA) cycle
coupled to the electron transport chain. Most energy in mammals is produced via TCA …
coupled to the electron transport chain. Most energy in mammals is produced via TCA …
Screening membraneless organelle participants with machine-learning models that integrate multimodal features
Protein self-assembly is one of the formation mechanisms of biomolecular condensates.
However, most phase-separating systems (PS) demand multiple partners in biological …
However, most phase-separating systems (PS) demand multiple partners in biological …
Eosinophil extracellular traps drive asthma progression through neuro-immune signals
Y Lu, Y Huang, J Li, J Huang, L Zhang, J Feng, J Li… - Nature Cell …, 2021 - nature.com
Eosinophilic inflammation is a feature of allergic asthma. Despite mounting evidence
showing that chromatin filaments released from neutrophils mediate various diseases, the …
showing that chromatin filaments released from neutrophils mediate various diseases, the …
Roadmap on digital holography-based quantitative phase imaging
Quantitative Phase Imaging (QPI) provides unique means for the imaging of biological or
technical microstructures, merging beneficial features identified with microscopy …
technical microstructures, merging beneficial features identified with microscopy …
Stress routes clients to the proteasome via a BAG2 ubiquitin-independent degradation condensate
DC Carrettiero, MC Almeida, AP Longhini… - Nature …, 2022 - nature.com
The formation of membraneless organelles can be a proteotoxic stress control mechanism
that locally condenses a set of components capable of mediating protein degradation …
that locally condenses a set of components capable of mediating protein degradation …
Phase separations in oncogenesis, tumor progressions and metastasis: a glance from hallmarks of cancer
LW Zheng, CC Liu, KD Yu - Journal of Hematology & Oncology, 2023 - Springer
Liquid–liquid phase separation (LLPS) is a novel principle for interpreting precise
spatiotemporal coordination in living cells through biomolecular condensate (BMC) …
spatiotemporal coordination in living cells through biomolecular condensate (BMC) …
M6A demethylase FTO-mediated downregulation of DACT1 mRNA stability promotes Wnt signaling to facilitate osteosarcoma progression
D Lv, S Ding, L Zhong, J Tu, H Li, H Yao, Y Zou, Z Zeng… - Oncogene, 2022 - nature.com
Despite advances in clinical diagnosis and treatment, the prognosis of patients with
osteosarcoma (OS) remains poor, and the treatment efficacy has plateaued. Therefore, it is …
osteosarcoma (OS) remains poor, and the treatment efficacy has plateaued. Therefore, it is …
Transforming growth factor-beta (TGF-β) in prostate cancer: A dual function mediator?
S Mirzaei, MDA Paskeh, Y Saghari, A Zarrabi… - International Journal of …, 2022 - Elsevier
Transforming growth factor-beta (TGF-β) is a member of a family of secreted cytokines with
vital biological functions in cells. The abnormal expression of TGF-β signaling is a common …
vital biological functions in cells. The abnormal expression of TGF-β signaling is a common …