Dengue fever is one of those unique diseases where host immune responses largely
determine the pathogenesis and its severity. Earlier studies have established the fact that …

Dengue is potentially a life-threatening arthropod-borne viral infection for which there are no
known therapeutic agents till date. Early stage diagnosis of dengue infection is still lacking …

Japanese encephalitis virus (JEV), a major cause of Japanese encephalitisis, is an
arbovirus that belongs to the genus Flavivirus of the family Flaviviridae. Currently, there is no …

Dengue outbreaks persist in global tropical regions, lacking approved antivirals,
necessitating critical therapeutic development against the virus. In this context, we …

Ethnopharmacological relevance Reduning injection (RDN), a patented traditional Chinese
medicine, has the obvious antipyretic effect and has been widely used in China. Although …

Abstract Background The outbreak of Coronavirus disease 2019 (COVID-19) has caused
more than 180 million infections and 3.9 million deaths. To date, emerging clinical evidence …

Objective To elucidate the anti-inflammatory mechanism of Reduning Injection (RDN) by
analyzing the potential biomarkers and metabolic pathways of the carrageenan-induced …

Dengue fever virus (DENV) is a global health threat that is becoming increasingly critical.
However, the pathogenesis of dengue has not yet been fully elucidated. In this study, we …

An estimated 3.9 billion individuals in 128 nations (about 40% of global population) are at
risk of acquiring dengue virus infection. About 390 million cases of dengue are reported …

Duck Tembusu virus (DTMUV), belonging to the Flaviviridae family, is a single-stranded
positive-sense RNA virus. Since April 2010, the outbreak of DTMUV in southeast provinces …