Vulvovaginal candidiasis: a current understanding and burning questions

HME Willems, SS Ahmed, J Liu, Z Xu, BM Peters - Journal of Fungi, 2020 - mdpi.com
Candida albicans, along with other closely related Candida species, are the primary
causative agents of vulvovaginal candidiasis (VVC)—a multifactorial infectious disease of …

Biofilms and vulvovaginal candidiasis

C Rodríguez-Cerdeira, MC Gregorio… - Colloids and Surfaces B …, 2019 - Elsevier
Candida species, including C. albicans, are part of the mucosal flora of most healthy women,
and inhabit the gastrointestinal and genitourinary tracts. Under favourable conditions, they …

Recent gene selection and drug resistance underscore clinical adaptation across Candida species

MÀ Schikora-Tamarit, T Gabaldón - Nature Microbiology, 2024 - nature.com
Understanding how microbial pathogens adapt to treatments, humans and clinical
environments is key to infer mechanisms of virulence, transmission and drug resistance …

Zinc Oxide Nanoparticles Inhibition of Initial Adhesion and ALS1 and ALS3 Gene Expression in Candida albicans Strains from Urinary Tract Infections

SS Hosseini, E Ghaemi, A Noroozi, F Niknejad - Mycopathologia, 2019 - Springer
Objective The aim of this study was to evaluate effects of zinc oxide nanoparticles (ZnO-np)
on initiation adhesion and agglutinin-like sequence (ALS) 1 and ALS3 gene expression …

Antimicrobial photodynamic therapy reduces gene expression of Candida albicans in biofilms

CC Jordão, TV de Sousa, MI Klein, LM Dias… - Photodiagnosis and …, 2020 - Elsevier
The present study evaluated whether the oxidative stress caused by antimicrobial
photodynamic therapy (aPDT) affects the expression of C. albicans genes related to …

In silico approaches for screening molecular targets in Candida albicans: A proteomic insight into drug discovery and development

DR Silva, JCO Sardi, IA Freires, ACB Silva… - European journal of …, 2019 - Elsevier
Candida species are opportunistic pathogens which can cause conditions ranging from
simple mucocutaneous infections to fungemia and death in immunosuppressed and …

Procatechuic acid and protocatechuic aldehyde increase survival of Caenorhabditis elegans after fungal infection and inhibit fungal virulence

C Yuan, Y Wang, L Zhang, D Wang - Frontiers in Pharmacology, 2024 - frontiersin.org
Protocatechuic acid (PCA) and protocatechuic aldehyde (PAL) are important phenolic
compounds in plants. We here investigated their possible beneficial effect against fungal …

Effects of Hsp90 Inhibitor Ganetespib on Inhibition of Azole-Resistant Candida albicans

R Yuan, J Tu, C Sheng, X Chen, N Liu - Frontiers in microbiology, 2021 - frontiersin.org
Candida albicans is the most common fungal pathogen. Recently, drug resistance of C.
albicans is increasingly severe. Hsp90 is a promising antifungal target to overcome this …

Evaluation of the antifungal effect of chlorogenic acid against strains of Candida spp. resistant to fluconazole: apoptosis induction and in silico analysis of the …

C Rocha da Silva, LGAV Sá… - Journal of Medical …, 2022 - microbiologyresearch.org
Introduction. Candida spp. are commensal fungal pathogens of humans, but when there is
an imbalance in the microbiota, or weak host immunity, these yeasts can become …

[HTML][HTML] Overexpression of MDR-1 and CDR-2 genes in fluconazole resistance of Candida albicans isolated from patients with vulvovaginal candidiasis

KK Rad, M Falahati, M Roudbary… - Current medical …, 2016 - ncbi.nlm.nih.gov
Background and Purpose: Candida albicans (C. albicans) is an opportunistic fungus that
can colonize women's mucosal epithelial cell surfaces, causing vulvovaginitis in specific …