Overview on the Effects of N-Acetylcysteine in Neurodegenerative Diseases
G Tardiolo, P Bramanti, E Mazzon - Molecules, 2018 - mdpi.com
N-acetylcysteine (NAC), which is an acetylated cysteine compound, has aroused scientific
interest for decades due to its important medical applications. It also represents a nutritional …
interest for decades due to its important medical applications. It also represents a nutritional …
[HTML][HTML] Neurosteroids as regulators of neuroinflammation
Neuroinflammation is a physiological protective response in the context of infection and
injury. However, neuroinflammation, especially if chronic, may also drive …
injury. However, neuroinflammation, especially if chronic, may also drive …
N‐acetylcysteine (NAC) in neurological disorders: mechanisms of action and therapeutic opportunities
R Bavarsad Shahripour, MR Harrigan… - Brain and …, 2014 - Wiley Online Library
Background There is an expanding field of research investigating the benefits of medicines
with multiple mechanisms of action across neurological disorders. N‐acetylcysteine (NAC) …
with multiple mechanisms of action across neurological disorders. N‐acetylcysteine (NAC) …
Role of reactive oxygen species (ROS) in apoptosis induction
HU Simon, A Haj-Yehia, F Levi-Schaffer - Apoptosis, 2000 - Springer
Reactive oxygen species (ROS) and mitochondria play an important role in apoptosis
induction under both physiologic and pathologic conditions. Interestingly, mitochondria are …
induction under both physiologic and pathologic conditions. Interestingly, mitochondria are …
Molecular mechanisms of N-acetylcysteine actions
M Zafarullah, WQ Li, J Sylvester, M Ahmad - Cellular and Molecular Life …, 2003 - Springer
Oxidative stress generated by an imbalance between reactive oxygen species (ROS) and
antioxidants contributes to the pathogenesis of arthritis, cancer, cardiovascular, liver and …
antioxidants contributes to the pathogenesis of arthritis, cancer, cardiovascular, liver and …
[PDF][PDF] Reactive oxygen species in tumor progression
P Storz - Front biosci, 2005 - researchgate.net
Introduction 3. Reactive oxygen species in tumor growth and cellular survival 4. Reactive
oxygen species in cell motility and metastasis formation 5. Generation of reactive oxygen …
oxygen species in cell motility and metastasis formation 5. Generation of reactive oxygen …
The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults
Lipid peroxidation has been implicated in a variety of pathophysiological processes,
including inflammation, atherogenesis, neurodegeneration, and the ageing process …
including inflammation, atherogenesis, neurodegeneration, and the ageing process …
Redox regulation of cellular signalling
H Kamata, H Hirata - Cellular signalling, 1999 - Elsevier
Extracellular stimuli elicit a variety of responses, such as cell proliferation and differentiation,
through the cellular signalling system. Binding of growth factors to the respective receptor …
through the cellular signalling system. Binding of growth factors to the respective receptor …
Oxidative stress and reactive oxygen species: a review of their role in ocular disease
For many years, oxidative stress arising from the ubiquitous production of reactive oxygen
species (ROS) has been implicated in the pathogenesis of various eye diseases. While …
species (ROS) has been implicated in the pathogenesis of various eye diseases. While …
Neurodegenerative disorders in humans: the role of glutathione in oxidative stress-mediated neuronal death
JS Bains, CA Shaw - Brain research reviews, 1997 - Elsevier
Oxidative stress has been implicated in both normal aging and in various
neurodegenerative disorders and may be a common mechanism underlying various forms …
neurodegenerative disorders and may be a common mechanism underlying various forms …