Extracellular matrix (ECM) molecules in the central nervous system form highly organized
ECM structures around cell somata, axon initial segments, and synapses and play …

During restricted time windows of postnatal life, called critical periods, neural circuits are
highly plastic and are shaped by environmental stimuli. In several mammalian brain areas …

Perineuronal nets (PNNs) are specialized extracellular matrix structures that surround
specific neurons in the brain and spinal cord, appear during critical periods of development …

The cerebellum, traditionally associated with motor coordination and balance, also plays a
crucial role in various aspects of higher-order function and dysfunction. Emerging research …

Matrix metalloproteinases (MMPs) are physiologically expressed in the central nervous
system in neurons, astrocytes and microglia, and their aberrant elevation contributes to a …

Perineuronal nets (PNNs) are assemblies of extracellular matrix molecules, which surround
the cell body and dendrites of many types of neuron and regulate neural plasticity. PNNs are …

Epilepsies are multifaceted neurological disorders characterized by abnormal brain activity,
eg caused by imbalanced synaptic excitation and inhibition. The neural extracellular matrix …

Fast-spiking parvalbumin interneurons are critical for the function of mature cortical inhibitory
circuits. Most of these neurons are enwrapped by a specialized extracellular matrix (ECM) …

The extracellular matrix (ECM) is a fundamental component of biological tissues. The ECM
in the central nervous system (CNS) is unique in both composition and function. Functions …

Tenascin C (TnC) is a glycoprotein highly expressed in the extracellular matrix (ECM) during
development and in the adult central nervous system (CNS) in regions of active …