Respiratory syncytial virus—a comprehensive review

AT Borchers, C Chang, ME Gershwin… - Clinical reviews in allergy …, 2013 - Springer
Respiratory syncytial virus (RSV) is amongst the most important pathogenic infections of
childhood and is associated with significant morbidity and mortality. Although there have …

Endoplasmic reticulum stress in immunity

SE Bettigole, LH Glimcher - Annual review of immunology, 2015 - annualreviews.org
Immune responses occur in the midst of a variety of cellular stresses that can severely
perturb endoplasmic reticulum (ER) function. The unfolded protein response is a three …

Interleukin‐13 in asthma pathogenesis

M Wills‐Karp - Immunological reviews, 2004 - Wiley Online Library
Bronchial asthma is a complex disorder that is thought to arise as a result of aberrant T‐
lymphocyte responses to noninfectious environmental antigens. In particular, the symptoms …

Immunity to RSV in early-life

L Lambert, AM Sagfors, PJM Openshaw… - Frontiers in …, 2014 - frontiersin.org
Respiratory Syncytial Virus (RSV) is the commonest cause of severe respiratory infection in
infants, leading to over 3 million hospitalizations and around 66,000 deaths worldwide each …

Evidence for a causal relationship between respiratory syncytial virus infection and asthma

P Wu, TV Hartert - Expert review of anti-infective therapy, 2011 - Taylor & Francis
Respiratory syncytial virus (RSV) infects all children early in life, is the most common cause
of infant lower respiratory tract infections, and causes disease exacerbations in children with …

[HTML][HTML] IL-17–induced pulmonary pathogenesis during respiratory viral infection and exacerbation of allergic disease

S Mukherjee, DM Lindell, AA Berlin, SB Morris… - The American journal of …, 2011 - Elsevier
Severe respiratory syncytial virus (RSV) infections are characterized by airway epithelial cell
damage, mucus hypersecretion, and Th2 cytokine production. Less is known about the role …

Mechanisms and treatments for severe, steroid‐resistant allergic airway disease and asthma

PM Hansbro, RY Kim, MR Starkey… - Immunological …, 2017 - Wiley Online Library
Severe, steroid‐resistant asthma is clinically and economically important since affected
individuals do not respond to mainstay corticosteroid treatments for asthma. Patients with …

Thymic stromal lymphopoietin is induced by respiratory syncytial virus–infected airway epithelial cells and promotes a type 2 response to infection

HC Lee, MB Headley, YM Loo, A Berlin… - Journal of Allergy and …, 2012 - Elsevier
BACKGROUND: Respiratory viral infection, including respiratory syncytial virus (RSV) and
rhinovirus, has been linked to respiratory disease in pediatric patients, including severe …

Differential role for TLR3 in respiratory syncytial virus-induced chemokine expression

BD Rudd, E Burstein, CS Duckett, X Li… - Journal of …, 2005 - Am Soc Microbiol
Respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract infection in
young infants worldwide. Previous studies have reported that the induction of interleukin …

Immune determinants of chronic sequelae after respiratory viral infection

H Narasimhan, Y Wu, NP Goplen, J Sun - Science Immunology, 2022 - science.org
The acute effects of various respiratory viral infections have been well studied, with
extensive characterization of the clinical presentation as well as viral pathogenesis and host …