Is adult neurogenesis essential for olfaction?

F Lazarini, PM Lledo - Trends in neurosciences, 2011 - cell.com
In mammals, new neurons are recruited into restricted brain areas throughout life. Adult-born
neurons produced in the subventricular zone of the lateral ventricle migrate rostrally towards …

Adult olfactory bulb neurogenesis

PM Lledo, M Valley - Cold Spring Harbor perspectives in …, 2016 - cshperspectives.cshlp.org
Most organisms use their olfactory system to detect and analyze chemical cues from the
external world to guide essential behaviors. From worms to vertebrates, chemicals are …

[HTML][HTML] Rapid online learning and robust recall in a neuromorphic olfactory circuit

N Imam, TA Cleland - Nature Machine Intelligence, 2020 - nature.com
We present a neural algorithm for the rapid online learning and identification of odourant
samples under noise, based on the architecture of the mammalian olfactory bulb and …

[HTML][HTML] Activation of adult-born neurons facilitates learning and memory

M Alonso, G Lepousez, S Wagner, C Bardy… - Nature …, 2012 - nature.com
Thousand of local interneurons reach the olfactory bulb of adult rodents every day, but the
functional effect of this process remains elusive. By selectively expressing channelrhodopsin …

The transcription factor Zif268/Egr1, brain plasticity, and memory

A Veyrac, A Besnard, J Caboche, S Davis… - Progress in molecular …, 2014 - Elsevier
The capacity to remember our past experiences and organize our future draws on a number
of cognitive processes that allow our brain to form and store neural representations that can …

Adult neurogenesis in Parkinson's disease

F Marxreiter, M Regensburger, J Winkler - Cellular and Molecular Life …, 2013 - Springer
Abstract Parkinson's disease (PD), the second most common neurodegenerative disorder,
affects 1–2% of humans aged 60 years and older. The diagnosis of PD is based on motor …

Continuous neurogenesis in the adult forebrain is required for innate olfactory responses

M Sakamoto, I Imayoshi, T Ohtsuka… - Proceedings of the …, 2011 - National Acad Sciences
Although the functional significance of adult neurogenesis in hippocampal-dependent
learning and memory has been well documented, the role of such neurogenesis in olfactory …

Brain size and limits to adult neurogenesis

MF Paredes, SF Sorrells… - Journal of …, 2016 - Wiley Online Library
The walls of the cerebral ventricles in the developing embryo harbor the primary neural stem
cells from which most neurons and glia derive. In many vertebrates, neurogenesis continues …

The impact of adult neurogenesis on olfactory bulb circuits and computations

G Lepousez, MT Valley, PM Lledo - Annual review of physiology, 2013 - annualreviews.org
Modern neuroscience has demonstrated how the adult brain has the ability to profoundly
remodel its neurons in response to changes in external stimuli or internal states. However …

Adult neurogenesis and the future of the rejuvenating brain circuits

G Lepousez, A Nissant, PM Lledo - Neuron, 2015 - cell.com
For a long time, the mammalian brain has been perceived to be a static organ. However, the
discovery of adult neurogenesis in most mammalian species, including humans, monkeys …