RNAi-based therapeutics and tumor targeted delivery in cancer
Over the past decade, non-coding RNA-based therapeutics have proven as a great potential
for the development of targeted therapies for cancer and other diseases. The discovery of …
for the development of targeted therapies for cancer and other diseases. The discovery of …
microRNA-382 as a tumor suppressor? Roles in tumorigenesis and clinical significance
MicroRNAs (miRNAs) are small single-stranded RNAs belonging to a class of non-coding
RNAs with an average length of 18–22 nucleotides. Although not able to encode any …
RNAs with an average length of 18–22 nucleotides. Although not able to encode any …
The role of microRNAs, long non-coding RNAs, and circular RNAs in cervical cancer
Prolonged infection of uterine cervix epithelium with human papillomavirus (HPV) and
constitutive expression of viral oncogenes have been recognized as the main cause of the …
constitutive expression of viral oncogenes have been recognized as the main cause of the …
Functional diversity of small nucleolar RNAs
T Bratkovič, J Božič, B Rogelj - Nucleic acids research, 2020 - academic.oup.com
Small nucleolar RNAs (snoRNAs) are short non-protein-coding RNAs with a long-
recognized role in tuning ribosomal and spliceosomal function by guiding ribose methylation …
recognized role in tuning ribosomal and spliceosomal function by guiding ribose methylation …
Emerging functions for snoRNAs and snoRNA-derived fragments
The widespread implementation of mass sequencing has revealed a diverse landscape of
small RNAs derived from larger precursors. Whilst many of these are likely to be byproducts …
small RNAs derived from larger precursors. Whilst many of these are likely to be byproducts …
Noncoding RNAs in extracellular fluids as cancer biomarkers: the new frontier of liquid biopsies
The last two decades of cancer research have been devoted in two directions:(1)
understanding the mechanism of carcinogenesis for an effective treatment, and (2) …
understanding the mechanism of carcinogenesis for an effective treatment, and (2) …
Let-7 as biomarker, prognostic indicator, and therapy for precision medicine in cancer
E Chirshev, KC Oberg, YJ Ioffe… - Clinical and translational …, 2019 - Springer
Abnormal regulation and expression of microRNAs (miRNAs) has been documented in
various diseases including cancer. The miRNA let-7 (MIRLET7) family controls …
various diseases including cancer. The miRNA let-7 (MIRLET7) family controls …
Insights on the potential oncogenic impact of long non-coding RNA nicotinamide nucleotide transhydrogenase antisense RNA 1 in different cancer types; integrating …
NM El-Sheikh, AI Abulsoud, EF Wasfey… - Pathology-Research and …, 2022 - Elsevier
Long non-coding RNAs (lncRNAs) are becoming more prevalent in the cancer field arena,
with functional roles in both oncogenic and onco-suppressive pathways. Despite their …
with functional roles in both oncogenic and onco-suppressive pathways. Despite their …
Exosomal-long non-coding RNAs journey in colorectal cancer: Evil and goodness faces of key players
Exosomes are nano-vesicles (NVs) secreted by cells and take part in cell-cell
communications. Lately, these exosomes were proved to have dual faces in cancer …
communications. Lately, these exosomes were proved to have dual faces in cancer …
A novel tRNA-derived fragment AS-tDR-007333 promotes the malignancy of NSCLC via the HSPB1/MED29 and ELK4/MED29 axes
W Yang, K Gao, Y Qian, Y Huang, Q Xiang… - Journal of hematology & …, 2022 - Springer
Background Transfer RNA-derived fragments (tRFs) are a new class of small non-coding
RNAs. Recent studies suggest that tRFs participate in some pathological processes …
RNAs. Recent studies suggest that tRFs participate in some pathological processes …