Hemophagocytic lymphohistiocytosis (HLH) is an overwhelming clinical syndrome
associated with extreme immune activation. Familial HLH is caused by autosomal-recessive …

Primary haemophagocytic lymphohistiocytosis (HLH) diseases are a collection of inherited
genetic disorders that cause the syndrome of HLH. Great advances have been made in the …

Allogeneic hematopoietic stem cell transplantation (HSCT) is a potentially curative treatment
for some inherited disorders, including selected primary immunodeficiencies (PIDs). In the …

Reduced-intensity conditioning has improved survival after hematopoietic stem cell
transplantation (HSCT) for hemophagocytic lymphohistiocytosis (HLH) at the cost of more …

The primary immunodeficiencies (PIDs), rare inherited diseases characterized by severe
dysfunction of immunity, have been successfully treated by allogeneic hematopoietic stem …

Reduced intensity conditioning (RIC) allogeneic hematopoietic cell transplantation (HCT)
with alemtuzumab, fludarabine, and melphalan is an effective approach for patients with …

Chronic graft-versus-host disease (cGVHD) remains a significant problem for patients after
allogeneic hematopoietic stem cell transplantation (allo-HSCT). Although in vivo …

Allogeneic hematopoietic stem cell transplantation (HSCT) is curative for many
nonmalignant pediatric disorders, including hemoglobinopathies, bone marrow failure …

The majority of children undergoing Hematopoietic Stem cell Transplantation (HSCT)
require conditioning therapy to make space and prevent rejection of the donor stem cells …

Haematopoietic stem cell transplantation currently remains the only curative treatment of
primary forms of haemophagocytic lymphohistiocytosis (HLH). Rapid diagnosis, efficient …