Oral squamous cell carcinomas: state of the field and emerging directions
Oral squamous cell carcinoma (OSCC) develops on the mucosal epithelium of the oral
cavity. It accounts for approximately 90% of oral malignancies and impairs appearance …
cavity. It accounts for approximately 90% of oral malignancies and impairs appearance …
The rediscovery of platinum-based cancer therapy
S Rottenberg, C Disler, P Perego - Nature Reviews Cancer, 2021 - nature.com
Platinum (Pt) compounds entered the clinic as anticancer agents when cisplatin was
approved in 1978. More than 40 years later, even in the era of precision medicine and …
approved in 1978. More than 40 years later, even in the era of precision medicine and …
NF-κB-HOTAIR axis links DNA damage response, chemoresistance and cellular senescence in ovarian cancer
AR Özeş, DF Miller, ON Özeş, F Fang, Y Liu, D Matei… - Oncogene, 2016 - nature.com
The transcription factor nuclear factor kappa B (NF-κB) and the long non-coding RNA
(lncRNA) HOTAIR (HOX transcript antisense RNA) have diverse functional roles in cancer …
(lncRNA) HOTAIR (HOX transcript antisense RNA) have diverse functional roles in cancer …
Precision medicine in head and neck cancer
Head and Neck cancer is among the most common cancers worldwide, with a high
prevalence in south East Asia, Brazil and central Europe. Head and Neck Squamous cell …
prevalence in south East Asia, Brazil and central Europe. Head and Neck Squamous cell …
Epigenetic modifications and head and neck cancer: implications for tumor progression and resistance to therapy
Head and neck squamous carcinoma (HNSCC) is the sixth most prevalent cancer and one
of the most aggressive malignancies worldwide. Despite continuous efforts to identify …
of the most aggressive malignancies worldwide. Despite continuous efforts to identify …
Epigenetic modifications in head and neck cancer
J Gaździcka, K Gołąbek, JK Strzelczyk… - Biochemical …, 2020 - Springer
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common human
malignancy in the world, with high mortality and poor prognosis for patients. Among the risk …
malignancy in the world, with high mortality and poor prognosis for patients. Among the risk …
Targeting the DNA Damage Response in OSCC with TP53 Mutations
A Lindemann, H Takahashi, AA Patel… - Journal of dental …, 2018 - journals.sagepub.com
Oral squamous cell carcinoma (OSCC) is the most common type of oral cancer worldwide
and in the United States. OSCC remains a major cause of morbidity and mortality in patients …
and in the United States. OSCC remains a major cause of morbidity and mortality in patients …
Effect of regulatory cell death on the occurrence and development of head and neck squamous cell carcinoma
Y Xue, X Jiang, J Wang, Y Zong, Z Yuan, S Miao… - Biomarker …, 2023 - Springer
Head and neck cancer is a malignant tumour with a high mortality rate characterized by late
diagnosis, high recurrence and metastasis rates, and poor prognosis. Head and neck …
diagnosis, high recurrence and metastasis rates, and poor prognosis. Head and neck …
Cell death in head and neck cancer pathogenesis and treatment
M Raudenská, J Balvan, M Masařík - Cell Death & Disease, 2021 - nature.com
Many cancer therapies aim to trigger apoptosis in cancer cells. Nevertheless, the presence
of oncogenic alterations in these cells and distorted composition of tumour …
of oncogenic alterations in these cells and distorted composition of tumour …
Cancer stem cells in head and neck squamous cell carcinoma: identification, characterization and clinical implications
C Peitzsch, J Nathansen, SI Schniewind, F Schwarz… - Cancers, 2019 - mdpi.com
Head and neck squamous cell carcinoma (HNSCC) is the sixth most commonly diagnosed
cancer worldwide. Despite advances in the treatment management, locally advanced …
cancer worldwide. Despite advances in the treatment management, locally advanced …