TGF‐β as a driver of fibrosis: physiological roles and therapeutic opportunities

EH Budi, JR Schaub, M Decaris, S Turner… - The Journal of …, 2021 - Wiley Online Library
Many chronic diseases are marked by fibrosis, which is defined by an abundance of
activated fibroblasts and excessive deposition of extracellular matrix, resulting in loss of …

Oral delivery of porous starch-loaded bilayer microgels for controlled drug delivery and treatment of ulcerative colitis

Z Wen, L Kang, H Fu, S Zhu, X Ye, X Yang… - Carbohydrate …, 2023 - Elsevier
We prepared one type of bilayer microgels for oral administration with three effects: pH
responsiveness, time lag, and colon enzyme degradation. Combined with the dual …

Preparation and evaluation of the doxazosin-bentonite composite as a pH-dependent controlled-release oral formulation

MJ Baek, HJ Shin, JH Park, J Kim, IM Kang, JI Lee… - Applied Clay …, 2022 - Elsevier
Bentonite (BT) is a natural clay mainly composed of montmorillonite which has
exchangeable cations in the interlayer space. BT has various advantages as a …

Bentonite as a water-insoluble amorphous solid dispersion matrix for enhancing oral bioavailability of poorly water-soluble drugs

MJ Baek, JH Park, DT Nguyen, D Kim, J Kim… - Journal of Controlled …, 2023 - Elsevier
Bentonite (BT), an orally administrable natural clay, is widely used for medical and
pharmaceutical purposes due to its unique properties, including swelling, adsorption and …

Effect of phosphatidylcholine in bentonite-quetiapine complex on enhancing drug release and oral bioavailability

MJ Baek, GH Kim, JH Park, J Kim, IM Kang… - International Journal of …, 2022 - Elsevier
Bentonite (BT) is a biocompatible clay mineral that has advantageous properties as a
pharmaceutical excipient. However, the application of BT in controlled-release oral …

[HTML][HTML] Combined Orobol-Bentonite Composite Formulation for Effective Topical Skin Targeted Therapy in Mouse Model

DT Nguyen, MH Kim, NY Yu, MJ Baek… - International Journal …, 2022 - ncbi.nlm.nih.gov
Purpose Orobol is an isoflavone that has a potent skin protection effect. The objective of this
study was to prepare a novel bentonite-based composite formulation of orobol to enhance …