The enterochromaffin-like [ECL] cell—Central in gastric physiology and pathology

HL Waldum, ØF Sørdal, PG Mjønes - International Journal of Molecular …, 2019 - mdpi.com
Background: Studies on the regulation of gastric and pancreatic secretion began more than
100 years ago. Secretin was the first hormone postulated to exist, initiating the field of …

A-like cells in the rat stomach contain ghrelin and do not operate under gastrin control

CD De La Cour, M Björkqvist, AK Sandvik, I Bakke… - Regulatory peptides, 2001 - Elsevier
Ghrelin is a 28 aa gastric peptide, recently identified as a natural ligand of the growth
hormone secretagogue receptor (orphan receptor distinct from the receptor for growth …

[HTML][HTML] Somatostatin analogs for gastric carcinoids: for many, but not all

S Massironi, A Zilli, D Conte - World journal of gastroenterology …, 2015 - ncbi.nlm.nih.gov
Gastric carcinoids (GCs) are classified as: type I, related to hypergastrinemia due to chronic
atrophic gastritis (CAG), type II, associated with Zollinger-Ellison syndrome in multiple …

Gastric endocrine tumors type I: treatment with long-acting somatostatin analogs

D Campana, F Nori, R Pezzilli… - Endocrine-related …, 2008 - erc.bioscientifica.com
Gastric endocrine tumors associated with autoimmune chronic atrophic gastritis (gastric
carcinoid type I) are almost exclusively benign lesions with little risk of deep invasion of the …

Treatment of ECL cell carcinoids with octreotide LAR

V Fykse, AK Sandvik, G Qvigstad… - Scandinavian journal …, 2004 - Taylor & Francis
Background: Patients with chronic atrophic gastritis (CAG) and hypergastrinaemia are at risk
of developing hyperplasia of the enterochromaffin‐like (ECL) cells and ECL‐cell‐derived …

Chronic treatment with somatostatin analogues in recurrent type 1 gastric neuroendocrine tumors

F Sebastian-Valles, B Bernaldo Madrid, C Sager… - Biomedicines, 2023 - mdpi.com
Background: Type 1 gastric neuroendocrine tumors (GC-1) represent an uncommon subtype
of neoplasms. Endoscopic resection has been proposed as the treatment of choice; active …

Gastric carcinoid

A Mulkeen, C Cha - Current opinion in oncology, 2005 - journals.lww.com
Despite the many advances that have been made in both the basic science and clinical
arenas, the optimal treatment of gastric carcinoid tumors is still a matter of debate. As the …

Expression of chromogranin A and somatostatin receptors in pancreatic AR42J cells

E Hofsli, L Thommesen, K Nørsett, S Falkmer… - Molecular and cellular …, 2002 - Elsevier
The exocrine pancreatic cell line AR42J is also known to display some neuroendocrine (NE)
features. We have extended this fact by showing that AR42J cells express mRNA of …

One-year follow-up study of patients with enterochromaffin-like cell carcinoids after treatment with octreotide long-acting release

V Fykse, A Kristian Sandvik… - Scandinavian journal of …, 2005 - Taylor & Francis
Objective. In a one-year study of 5 patients with chronic atrophic gastritis (CAG), pernicious
anaemia (PA), hypergastrinaemia and enterochromaffin-like (ECL) cell tumours, the …

Gastrin upregulates the prosurvival factor secretory clusterin in adenocarcinoma cells and in oxyntic mucosa of hypergastrinemic rats

CS Fjeldbo, I Bakke, SE Erlandsen… - American Journal …, 2012 - journals.physiology.org
We show that the gastric hormone gastrin induces the expression of the prosurvival
secretory clusterin (sCLU) in rat adenocarcinoma cells. Clusterin mRNA was still …