Electrochemiluminescence metal-organic frameworks biosensing materials for detecting cancer biomarkers

B Mohan, S Kumar, V Kumar, T Jiao, HK Sharma… - TrAC Trends in …, 2022 - Elsevier
Early detection of severe diseases like cancer is an urgent need for public health and safety.
It can determine by using synthesized materials for sensing cancer biomarkers …

Acute kidney injury: medical causes and pathogenesis

F Turgut, AS Awad, EM Abdel-Rahman - Journal of Clinical Medicine, 2023 - mdpi.com
Acute kidney injury (AKI) is a common clinical syndrome characterized by a sudden decline
in or loss of kidney function. AKI is not only associated with substantial morbidity and …

Cellular pathophysiology of ischemic acute kidney injury

JV Bonventre, L Yang - The Journal of clinical investigation, 2011 - Am Soc Clin Investig
Ischemic kidney injury often occurs in the context of multiple organ failure and sepsis. Here,
we review the major components of this dynamic process, which involves hemodynamic …

[HTML][HTML] Molecular characterization of the transition from acute to chronic kidney injury following ischemia/reperfusion

J Liu, S Kumar, E Dolzhenko, GF Alvarado, J Guo… - JCI insight, 2017 - ncbi.nlm.nih.gov
Though an acute kidney injury (AKI) episode is associated with an increased risk of chronic
kidney disease (CKD), the mechanisms determining the transition from acute to irreversible …

A basic science view of acute kidney injury biomarkers

JR Charlton, D Portilla, MD Okusa - Nephrology Dialysis …, 2014 - academic.oup.com
Over the last decade, significant progress has been made in the identification and validation
of novel biomarkers as well as refinements in the use of serum creatinine as a marker of …

Next-generation biomarkers for detecting kidney toxicity

JV Bonventre, VS Vaidya, R Schmouder, P Feig… - Nature …, 2010 - nature.com
Next-generation biomarkers for detecting kidney toxicity | Nature Biotechnology Skip to
main content Thank you for visiting nature.com. You are using a browser version with …

[HTML][HTML] Discovery and validation of miR-452 as an effective biomarker for acute kidney injury in sepsis

Z Liu, D Yang, J Gao, X Xiang, X Hu, S Li, W Wu… - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Sepsis is the cause of nearly half of acute kidney injury (AKI) and, unfortunately,
AKI in sepsis is associated with unacceptably high rates of mortality. Early detection of AKI …

Kidney injury molecule-1 (KIM-1): a urinary biomarker and much more

JV Bonventre - Nephrology Dialysis Transplantation, 2009 - academic.oup.com
6. Jain AK, McLeod I, Huo C et al. When laboratories report estimated glomerular filtration
rates in addition to serum creatinines, nephrology consults increase. Kidney Int 2009 May 13 …

[HTML][HTML] Drug-induced nephrotoxicity and its biomarkers

SY Kim, A Moon - Biomolecules & therapeutics, 2012 - ncbi.nlm.nih.gov
Nephrotoxicity occurs when kidney-specific detoxification and excretion do not work properly
due to the damage or destruction of kidney function by exogenous or endogenous toxicants …

More than a simple biomarker: the role of NGAL in cardiovascular and renal diseases

M Buonafine, E Martinez-Martinez, F Jaisser - Clinical science, 2018 - portlandpress.com
Neutrophil gelatinase-associated lipocalin (NGAL) is a small circulating protein that is highly
modulated in a wide variety of pathological situations, making it a useful biomarker of …