Advances in nanomedicines for lymphatic imaging and therapy
Lymph nodes play a pivotal role in tumor progression as key components of the lymphatic
system. However, the unique physiological structure of lymph nodes has traditionally …
system. However, the unique physiological structure of lymph nodes has traditionally …
[HTML][HTML] Role of lymphatic endothelial cells in the tumor microenvironment—a narrative review of recent advances
M He, Q He, X Cai, Z Chen, S Lao, H Deng… - … lung cancer research, 2021 - ncbi.nlm.nih.gov
Background As lymphatic vessel is a major route for solid tumor metastasis, they are
considered an essential part of tumor drainage conduits. Apart from forming the walls of …
considered an essential part of tumor drainage conduits. Apart from forming the walls of …
Targeted micellar phthalocyanine for lymph node metastasis homing and photothermal therapy in an orthotopic colorectal tumor model
Highlights Small-sized trastuzumab-targeted micelles (T-MP) were engineered using a
surfactant-stripping approach that yielded concentrated phthalocyanines with strong near …
surfactant-stripping approach that yielded concentrated phthalocyanines with strong near …
Subcutaneous drug delivery from nanoscale systems
L Tomasini, M Ferrere, J Nicolas - Nature Reviews Bioengineering, 2024 - nature.com
Various types of nanoscale drug delivery systems (DDSs) have been developed for
therapeutic and/or diagnostic applications. However, most systems have been designed for …
therapeutic and/or diagnostic applications. However, most systems have been designed for …
The lymphatic system and pancreatic cancer
DM Fink, MM Steele, MA Hollingsworth - Cancer letters, 2016 - Elsevier
This review summarizes current knowledge of the biology, pathology and clinical
understanding of lymphatic invasion and metastasis in pancreatic cancer. We discuss the …
understanding of lymphatic invasion and metastasis in pancreatic cancer. We discuss the …
Lymphatic changes in cancer and drug delivery to the lymphatics in solid tumors
Although many solid tumors use the lymphatic system to metastasize, there are few
treatment options that directly target cancer present in the lymphatic system, and those that …
treatment options that directly target cancer present in the lymphatic system, and those that …
Vitamin D suppresses ovarian cancer growth and invasion by targeting long non-coding RNA CCAT2
Ovarian cancer is the most deadly gynecologic cancer among women worldwide. Poor
response to current treatment makes it necessary to discover new diagnostic biomarkers to …
response to current treatment makes it necessary to discover new diagnostic biomarkers to …
Pep-1&borneol–bifunctionalized carmustine-loaded micelles enhance anti-glioma efficacy through tumor-targeting and BBB-penetrating
X Guo, G Wu, H Wang, L Chen - Journal of pharmaceutical sciences, 2019 - Elsevier
Tumor-targeting and blood-brain barrier (BBB)-penetrating are highly desirable for the
treatment of glioma. In this study, we developed Pep-1&borneol–bifunctionalized carmustine …
treatment of glioma. In this study, we developed Pep-1&borneol–bifunctionalized carmustine …
Near-infrared upconversion multimodal nanoparticles for targeted radionuclide therapy of breast cancer lymphatic metastases
C Zhang, Y Zhang, M Liang, X Shi, Y Jun… - Frontiers in …, 2022 - frontiersin.org
The theranostics of lymph node metastasis has always been one of the major obstacles to
defeating breast cancer and an important decisive factor in the prognosis of patients. Herein …
defeating breast cancer and an important decisive factor in the prognosis of patients. Herein …
Nanomaterial-based drug delivery system targeting lymph nodes
Z Cheng, H Que, L Chen, Q Sun, X Wei - Pharmaceutics, 2022 - mdpi.com
The lymphatic system plays an indispensable role in humoral balance, lipid metabolism, and
immune regulation. The lymph nodes (LNs) are known as the primary sites of tumor …
immune regulation. The lymph nodes (LNs) are known as the primary sites of tumor …