Molecular mechanism involved in cyclophosphamide-induced cardiotoxicity: Old drug with a new vision
Cyclophosphamide (CP) is an important anticancer drug which belongs to the class of
alkylating agent. Cyclophosphamide is mostly used in bone marrow transplantation …
alkylating agent. Cyclophosphamide is mostly used in bone marrow transplantation …
Carotenoids, inflammation, and oxidative stress—implications of cellular signaling pathways and relation to chronic disease prevention
A Kaulmann, T Bohn - Nutrition research, 2014 - Elsevier
Several epidemiologic studies have shown that diets rich in fruits and vegetables reduce the
risk of developing several chronic diseases, such as type 2 diabetes, atherosclerosis, and …
risk of developing several chronic diseases, such as type 2 diabetes, atherosclerosis, and …
Naringin protects against cyclophosphamide-induced hepatotoxicity and nephrotoxicity through modulation of oxidative stress, inflammation, apoptosis, autophagy …
Cyclophosphamide (CP) is a common chemotherapeutic agent that is effective against a
wide variety of tumors. The associated hepatotoxicity and nephrotoxicity, however, limit its …
wide variety of tumors. The associated hepatotoxicity and nephrotoxicity, however, limit its …
Orange fruit (Citrus sinensis) peel extract attenuates chemotherapy-induced toxicity in male rats
EA Abdelghffar, HAS El-Nashar, AGA Al-Mohammadi… - Food & function, 2021 - pubs.rsc.org
Background: Cyclophosphamide (CYP) is a chemotherapy drug widely used in the treatment
of several types of cancers and autoimmune disorders. Unfortunately, it causes severe side …
of several types of cancers and autoimmune disorders. Unfortunately, it causes severe side …
Crocin: A fighter against inflammation and pain
Crocin, a water-soluble carotenoid, is known as a pharmacologically active compound,
particularly for its potent anti-oxidant activity. The present work provides a comprehensive …
particularly for its potent anti-oxidant activity. The present work provides a comprehensive …
Saffron: the golden spice with therapeutic properties on digestive diseases
Saffron is a natural compound that has been used for centuries in many parts of the world as
a food colorant and additive. It was shown to have the ability to mitigate various disorders …
a food colorant and additive. It was shown to have the ability to mitigate various disorders …
A Perspective on Crocus sativus L. (Saffron) Constituent Crocin: A Potent Water-Soluble Antioxidant and Potential Therapy for Alzheimer's Disease
JW Finley, S Gao - Journal of agricultural and food chemistry, 2017 - ACS Publications
Alzheimer's disease (AD) is the most common form of dementia, in which the death of brain
cells causes memory loss and cognitive decline. Several factors are thought to play roles in …
cells causes memory loss and cognitive decline. Several factors are thought to play roles in …
[HTML][HTML] Therapeutic effects of saffron (Crocus sativus L.) in digestive disorders: a review
AR Khorasany, H Hosseinzadeh - Iranian journal of basic medical …, 2016 - ncbi.nlm.nih.gov
Saffron, the dried red-orange stigmas of Crocus sativus L, has been known as a flavoring
agent, food coloring and traditional herbal medicine. Pharmacological effects of saffron are …
agent, food coloring and traditional herbal medicine. Pharmacological effects of saffron are …
Crocin inhibits the migration, invasion, and epithelial‐mesenchymal transition of gastric cancer cells via miR‐320/KLF5/HIF‐1α signaling
Y Zhou, Q Xu, J Shang, L Lu… - Journal of cellular …, 2019 - Wiley Online Library
The biological activities of crocin, one of the main bioactive compounds of saffron, include
anti‐inflammatory, antioxidant, antidepressant, and anticancer effects. Crocin has been …
anti‐inflammatory, antioxidant, antidepressant, and anticancer effects. Crocin has been …
Hesperidin protects against cyclophosphamide-induced hepatotoxicity by upregulation of PPARγ and abrogation of oxidative stress and inflammation
AM Mahmoud - Canadian journal of physiology and …, 2014 - cdnsciencepub.com
The most important reason for the non-approval and withdrawal of drugs by the Food and
Drug Administration is hepatotoxicity. Therefore, this study was undertaken to evaluate the …
Drug Administration is hepatotoxicity. Therefore, this study was undertaken to evaluate the …