[HTML][HTML] Interplay between inflammation and thrombosis in cardiovascular pathology
K Stark, S Massberg - Nature Reviews Cardiology, 2021 - nature.com
Thrombosis is the most feared complication of cardiovascular diseases and a main cause of
death worldwide, making it a major health-care challenge. Platelets and the coagulation …
death worldwide, making it a major health-care challenge. Platelets and the coagulation …
[HTML][HTML] A review of neutrophil extracellular traps (NETs) in disease: potential anti-NETs therapeutics
V Mutua, LJ Gershwin - Clinical reviews in allergy & immunology, 2021 - Springer
Activated neutrophils release neutrophil extracellular traps (NETs) in response to a variety of
stimuli. NETosis is driven by protein-arginine deiminase type 4, with the release of …
stimuli. NETosis is driven by protein-arginine deiminase type 4, with the release of …
[HTML][HTML] Vascular occlusion by neutrophil extracellular traps in COVID-19
M Leppkes, J Knopf, E Naschberger, A Lindemann… - …, 2020 - thelancet.com
Background Coronavirus induced disease 2019 (COVID-19) can be complicated by severe
organ damage leading to dysfunction of the lungs and other organs. The processes that …
organ damage leading to dysfunction of the lungs and other organs. The processes that …
Neutrophil extracellular traps: from physiology to pathology
At the frontline of the host defence response, neutrophil antimicrobial functions have
adapted to combat infections and injuries of different origins and magnitude. The release of …
adapted to combat infections and injuries of different origins and magnitude. The release of …
[HTML][HTML] Devilishly radical NETwork in COVID-19: Oxidative stress, neutrophil extracellular traps (NETs), and T cell suppression
G Schönrich, MJ Raftery, Y Samstag - Advances in biological regulation, 2020 - Elsevier
Abstract Pandemic coronavirus disease 2019 (COVID-19) is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and poses an unprecedented challenge …
respiratory syndrome coronavirus 2 (SARS-CoV-2) and poses an unprecedented challenge …
Neutrophil extracellular traps participate in cardiovascular diseases: recent experimental and clinical insights
Neutrophil extracellular traps (NETs) have recently emerged as a newly recognized
contributor to venous and arterial thrombosis. These strands of DNA extruded by activated or …
contributor to venous and arterial thrombosis. These strands of DNA extruded by activated or …
Coagulation and sepsis
M Levi, T van der Poll - Thrombosis research, 2017 - Elsevier
Severe sepsis is almost invariably associated with systemic activation of coagulation. There
is ample evidence that demonstrates a wide-ranging cross-talk between hemostasis and …
is ample evidence that demonstrates a wide-ranging cross-talk between hemostasis and …
Ligand-targeted drug delivery
M Srinivasarao, PS Low - Chemical reviews, 2017 - ACS Publications
Safety and efficacy constitute the major criteria governing regulatory approval of any new
drug. The best method to maximize safety and efficacy is to deliver a proven therapeutic …
drug. The best method to maximize safety and efficacy is to deliver a proven therapeutic …
Neutrophils as protagonists and targets in chronic inflammation
O Soehnlein, S Steffens, A Hidalgo… - Nature Reviews …, 2017 - nature.com
Traditionally, neutrophils have been acknowledged to be the first immune cells that are
recruited to an inflamed tissue and have mainly been considered in the context of acute …
recruited to an inflamed tissue and have mainly been considered in the context of acute …
[PDF][PDF] Neutrophil extracellular traps: the biology of chromatin externalization
G Sollberger, DO Tilley, A Zychlinsky - Developmental cell, 2018 - cell.com
Neutrophils are essential to the homeostatic mission of safeguarding host tissues,
responding rapidly and diversely to breaches of the host's barriers to infection, and returning …
responding rapidly and diversely to breaches of the host's barriers to infection, and returning …