Schistosomiasis—from immunopathology to vaccines
DP McManus, R Bergquist, P Cai… - Seminars in …, 2020 - Springer
Schistosomiasis (bilharzia) is a neglected tropical disease caused by trematode worms of
the genus Schistosoma. The transmission cycle involves human (or other mammalian) water …
the genus Schistosoma. The transmission cycle involves human (or other mammalian) water …
Current status of vaccines for schistosomiasis
DP McManus, A Loukas - Clinical microbiology reviews, 2008 - Am Soc Microbiol
Schistosomiasis, caused by trematode blood flukes of the genus Schistosoma, is recognized
as the most important human helminth infection in terms of morbidity and mortality. Infection …
as the most important human helminth infection in terms of morbidity and mortality. Infection …
[HTML][HTML] Extracellular vesicles secreted by Schistosoma mansoni contain protein vaccine candidates
Herein we show for the first time that Schistosoma mansoni adult worms secrete exosome-
like extracellular vesicles ranging from 50 to 130 nm in size. Extracellular vesicles were …
like extracellular vesicles ranging from 50 to 130 nm in size. Extracellular vesicles were …
Schistosomiasis vaccines: where do we stand?
Schistosomiasis, caused mainly by S. mansoni, S. haematobium and S. japonicum,
continues to be a serious tropical disease and public health problem resulting in an …
continues to be a serious tropical disease and public health problem resulting in an …
Developing vaccines to combat hookworm infection and intestinal schistosomiasis
Hookworm infection and schistosomiasis rank among the most important health problems in
developing countries. Both cause anaemia and malnutrition, and schistosomiasis also …
developing countries. Both cause anaemia and malnutrition, and schistosomiasis also …
Schistosomiasis in the People's Republic of China: the era of the Three Gorges Dam
DP McManus, DJ Gray, Y Li, Z Feng… - Clinical microbiology …, 2010 - Am Soc Microbiol
The potential impact of the Three Gorges Dam (TGD) on schistosomiasis transmission in
China has invoked considerable global concern. The TGD will result in changes in the water …
China has invoked considerable global concern. The TGD will result in changes in the water …
Carcinogenic liver fluke secretes extracellular vesicles that promote cholangiocytes to adopt a tumorigenic phenotype
Abstract Background. Throughout Asia, there is an unprecedented link between
cholangiocarcinoma and infection with the liver fluke Opisthorchis viverrini. Multiple …
cholangiocarcinoma and infection with the liver fluke Opisthorchis viverrini. Multiple …
Vaccines to combat the neglected tropical diseases
JM Bethony, RN Cole, X Guo, S Kamhawi… - Immunological …, 2011 - Wiley Online Library
The neglected tropical diseases (NTDs) represent a group of parasitic and related infectious
diseases such as amebiasis, Chagas disease, cysticercosis, echinococcosis, hookworm …
diseases such as amebiasis, Chagas disease, cysticercosis, echinococcosis, hookworm …
[HTML][HTML] A quantitative proteomic analysis of the tegumental proteins from Schistosoma mansoni schistosomula reveals novel potential therapeutic targets
The tegument of Schistosoma mansoni plays an integral role in host–parasite interactions,
particularly during the transition from the free-living cercariae to the intra-mammalian …
particularly during the transition from the free-living cercariae to the intra-mammalian …
Proteome analysis of the surface of Trichomonas vaginalis reveals novel proteins and strain-dependent differential expression
The identification of surface proteins on the plasma membrane of pathogens is of
fundamental importance in understanding host-pathogen interactions. Surface proteins of …
fundamental importance in understanding host-pathogen interactions. Surface proteins of …