Rheumatoid arthritis and the mucosal origins hypothesis: protection turns to destruction

VM Holers, MK Demoruelle, KA Kuhn… - Nature Reviews …, 2018 - nature.com
Individuals at high risk of developing seropositive rheumatoid arthritis (RA) can be identified
for translational research and disease prevention studies through the presence of highly …

Diagnosis and management of rheumatoid arthritis

AM Wasserman - American family physician, 2011 - aafp.org
Rheumatoid arthritis is the most commonly diagnosed systemic inflammatory arthritis.
Women, smokers, and those with a family history of the disease are most often affected …

EULAR recommendations for the use of imaging of the joints in the clinical management of rheumatoid arthritis

AN Colebatch, CJ Edwards, M Østergaard… - Annals of the …, 2013 - ard.bmj.com
Objective To develop evidence-based recommendations on the use of imaging of the joints
in the clinical management of rheumatoid arthritis (RA). Methods The task force comprised …

Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage

J Shi, R Knevel, P Suwannalai… - Proceedings of the …, 2011 - National Acad Sciences
Autoimmune responses against posttranslationally modified antigens are a hallmark of
several autoimmune diseases. For example, antibodies against citrullinated protein antigens …

Autoantibody epitope spreading in the pre-clinical phase predicts progression to rheumatoid arthritis

J Sokolove, R Bromberg, KD Deane, LJ Lahey… - PloS one, 2012 - journals.plos.org
Rheumatoid arthritis (RA) is a prototypical autoimmune arthritis affecting nearly 1% of the
world population and is a significant cause of worldwide disability. Though prior studies …

Long‐term impact of delay in assessment of patients with early arthritis

MPM Van Der Linden, S Le Cessie… - Arthritis & …, 2010 - Wiley Online Library
Objective During the last decade, rheumatologists have learned to initiate disease‐
modifying antirheumatic drugs (DMARDs) early to improve the outcome of rheumatoid …

Predicting the development of clinical arthritis in anti-CCP positive individuals with non-specific musculoskeletal symptoms: a prospective observational cohort study

C Rakieh, JL Nam, L Hunt, EMA Hensor… - Annals of the …, 2015 - ard.bmj.com
Objectives To monitor progression to inflammatory arthritis (IA) in individuals with non-
specific musculoskeletal (MSK) symptoms and positive anticyclic citrullinated peptide (anti …

Classification of rheumatoid arthritis: comparison of the 1987 American College of Rheumatology criteria and the 2010 American College of Rheumatology/European …

MPM Van der Linden, R Knevel… - Arthritis & …, 2011 - Wiley Online Library
Objective New criteria to classify rheumatoid arthritis (RA) have been derived in order to
increase the specificity and sensitivity for early RA compared with the 1987 American …

Efficacy of methotrexate treatment in patients with probable rheumatoid arthritis: a double‐blind, randomized, placebo‐controlled trial

H van Dongen, J van Aken, LR Lard… - Arthritis & …, 2007 - Wiley Online Library
Objective To determine whether patients with undifferentiated arthritis (UA; inflammatory,
nontraumatic arthritis that cannot be diagnosed using current classification criteria) benefit …

Predicting arthritis outcomes—what can be learned from the Leiden Early Arthritis Clinic?

DPC de Rooy, MPM van der Linden, R Knevel… - …, 2011 - academic.oup.com
Objectives. In order to allow personalized medicine, adequate prediction of disease
outcome is required. In early undifferentiated arthritis (UA), prediction of the development of …