HIV infection can be effectively treated by lifelong administration of combination antiretroviral
therapy, but an effective vaccine will likely be required to end the HIV epidemic. Although the …

Analytical antiretroviral treatment interruption (ATI) is an important feature of HIV research,
seeking to achieve sustained viral suppression in the absence of antiretroviral therapy (ART) …

Introduction: Knowledge of HIV status relies on accurate HIV testing, and is the first step
towards access to HIV treatment and prevention programmes. Globally, HIV-status …

Despite promising results in preclinical studies, only a handful of clinical trials have been
initiated worldwide. Several obstacles remain prior to successful application of HIV-specific …

Many broadly neutralizing antibodies (bnAbs) targeting the HIV-1 envelope glycoprotein are
being assessed in clinical trials as strategies for HIV-1 prevention, treatment, and …

Introduction: The search for an HIV cure involves important behavioural and social
processes that complement the domains of biomedicine. However, the field has yet to tap …

Most people living with HIV (PLHIV) with reliable access to antiretroviral treatment (ART)
have a life expectancy similar to uninfected populations. Despite this, HIV can negatively …

Participation in HIV cure-related clinical trials that involve antiretroviral treatment (ART)
interruption may pose substantial individual risks for people living with HIV (PLHIV) without …

Treatment interruption trials are a vital tool, but their optimal design remain uncertain and
must balance participant risks with scientific rigor. The ability to predict the timing or extent of …

Introduction The question of what motivates people to participate in research is particularly
salient in the HIV field. While participation in HIV research was driven by survival in the …