Carbonic anhydrase inhibitors—part 52. Metal complexes of heterocyclic sulfonamides: a new class of strong topical intraocular pressure-lowering agents in rabbits

CT Supuran, F Mincione, A Scozzafava… - European journal of …, 1998 - Elsevier
A new sulfonamide possessing strong carbonic anhydrase (CA) inhibitory properties has
been prepared by reaction of 5-amino-1, 3, 4-thiadiazole-2-sulfonamide with adamantyl-1 …

[HTML][HTML] Alpha-glucosidase and carbonic anhydrase inhibition studies of Pd (II)-hydrazide complexes

U Ashiq, RA Jamal, M Saleem… - Arabian Journal of …, 2017 - Elsevier
This study focused on the synthesis and characterization of hydrazide ligands and their
respective Pd (II) complexes and used high throughput screening to determine their α …

Novel aromatic/heterocyclic sulfonamides and their metal complexes as inhibitors of carbonic anhydraseisozymes I, II and IV

CT Supuran, A Scozzafava - Journal of enzyme inhibition, 1997 - Taylor & Francis
Reaction of five aromatic/heterocyclic sulfonamides containing free amino, groups with 5-
nitro-α-2-toluenesultone and diethyl pyrocarbonate, respectively, afforded novel inhibitors of …

Organoruthenium (II) complexes of acetazolamide potently inhibit human carbonic anhydrase isoforms I, II, IX and XII

S Seršen, K Traven, J Kljun, I Turel… - Journal of enzyme …, 2019 - Taylor & Francis
Two acetazolamide (AAZ) complexes with ruthenium (II) η6-p-cymene chloride were
synthesised, characterised and tested for their inhibitory effects on several carbonic …

New sulfonamides containing organometallic-acylhydrazones: synthesis, characterisation and biological evaluation as inhibitors of human carbonic anhydrases

Y Huentupil, L Peña, N Novoa, E Berrino… - Journal of Enzyme …, 2019 - Taylor & Francis
A series of organometallic acylhydrazones was prepared, incorporating Re (CO) 3, Mn (CO)
3 and ferrocenyl moieties, which were subsequently reacted with amino-sulfonamides in …

Carbonic anhydrase inhibitors. Schiff bases of some aromatic sulfonamides and their metal complexes: towards more selective inhibitors of carbonic anhydrase …

A Popescu, A Simion, A Scozzafava… - Journal of enzyme …, 1999 - Taylor & Francis
Reaction of three aromatic sulfonamides possessing a primary amino group, ie,
sulfanilamide, homosulfanilamide and p-aminoethyl-benzenesulfonamide with heterocyclic …

Synthesis, characterization and in vitro inhibition of metal complexes of pyrazole based sulfonamide on human erythrocyte carbonic anhydrase isozymes I and II

N Büyükkıdan, B Büyükkıdan, M Bülbül… - Journal of Enzyme …, 2017 - Taylor & Francis
Sulfonamides represent an important class of biologically active compounds. A sulfonamide
possessing carbonic anhydrase (CA) inhibitory properties obtained from a pyrazole based …

[PDF][PDF] Complexes with biologically active ligands. Part 8. Synthesis and carbonic anhydrase inhibitory activity of 5-benzoylamido-and 5-(3-nitrobenzoylamido)-1, 3, 4 …

A Jitianu, MA Ilies, A Scozzafava… - Main Group Met …, 1997 - degruyter.com
Complexes containing the anions of 5-benzoylamido-l, 3, 4-thiadiazole-2-sulfonamide and 5-
(3-nitrobenzoylamido)-l, 3, 4-thiadiazole-2-sulfonamide as ligands, and main group metal …

Complexes With Biologically Active Ligands. Part 101 Inhibition of Carbonic Anhydrase Isozymes I and II With Metal Complexes of Imidazo[2, 1 − b]‐1,3,4 …

A Scozzafava, CT Supuran - Metal‐Based Drugs, 1997 - Wiley Online Library
The title compound was prepared by an improved variant of the literature procedure, and
metal complexes containing its anion and the following metal ions: Zn (II), Cd (II), Hg (II), Co …

Carbonic Anhydrase Inhibitors. Part 461 Inhibition of Carbonic Anhydrase Isozymes I, II and IV With Trifluoromethylsulfonamide Derivatives and Their Zinc(II) and …

G Mincione, A Scozzafava, CT Supuran - Metal‐Based Drugs, 1997 - Wiley Online Library
Reaction of aromatic/heterocyclic sulfonamides containing a free amino group with triflic
anhydride afforded compounds possessing trifluoromethanesulfonamido moieties in their …