Multifaceted roles of copper ions in anticancer nanomedicine
S Yang, Y Song, Y Hu, HJ Chen… - Advanced Healthcare …, 2023 - Wiley Online Library
The significantly increased copper level in tumor tissues and serum indicates the close
association of copper ions with tumor development, making copper ions attractive targets in …
association of copper ions with tumor development, making copper ions attractive targets in …
Nanomedicine targets endogenous copper ions for disease diagnosis and therapy
X Li, Y Cui, T Zhou, J Li, P Lu, L Yuwen, L Wang… - Chemical Engineering …, 2023 - Elsevier
Copper ion is an essential microelement that plays vital roles in a wide range of
physiological processes, and aberrant copper levels in vivo usually cause various diseases …
physiological processes, and aberrant copper levels in vivo usually cause various diseases …
Identification of a novel cuproptosis-related gene signature for prognostic implication in head and neck squamous carcinomas
S Tang, L Zhao, XB Wu, Z Wang, LY Cai, D Pan, Y Li… - Cancers, 2022 - mdpi.com
Simple Summary Head and neck squamous carcinoma (HNSC) is a common malignancy
that requires novel therapeutic targets. Cuproptosis is an emerging research hotspot. The …
that requires novel therapeutic targets. Cuproptosis is an emerging research hotspot. The …
Addressing the gaps in homeostatic mechanisms of copper and copper dithiocarbamate complexes in cancer therapy: a shift from classical platinum-drug …
The platinum drug, cisplatin, is considered as among the most successful medications in
cancer treatment. However, due to its inherent toxicity and resistance limitations, research …
cancer treatment. However, due to its inherent toxicity and resistance limitations, research …
Prognostic prediction of head and neck squamous cell carcinoma: Construction of cuproptosis‐related long non‐coding RNA signature
Q Huang, Q You, N Zhu, Z Wu, Z Xiang… - Journal of Clinical …, 2022 - Wiley Online Library
Background Recently, a new type of programmed cell death, cuproptosis, has been
identified to play important role in the progression of tumors. We constructed a cuproptosis …
identified to play important role in the progression of tumors. We constructed a cuproptosis …
Identification and validation of novel lung adenocarcinoma subtypes and construction of prognostic models: based on cuprotosis-related genes
G Wang, A Wang, L Wang, G Xu, X Hong… - BMC pulmonary …, 2023 - Springer
Cuprotosis is a novel and unique form of cell death that is of great value in a variety of
cancers. However, the prognostic role of cuprotosis-related genes (CRGs) in lung cancer …
cancers. However, the prognostic role of cuprotosis-related genes (CRGs) in lung cancer …
Role of copper chelating agents: between old applications and new perspectives in neuroscience
R Leuci, L Brunetti, V Tufarelli, M Cerini… - Neural Regeneration …, 2025 - journals.lww.com
The role of copper element has been an increasingly relevant topic in recent years in the
fields of human and animal health, for both the study of new drugs and innovative food and …
fields of human and animal health, for both the study of new drugs and innovative food and …
Cu(bta)(1,10-phen)ClO4 copper complex modulates the carcinogenicity of carboplatin in somatic cells of Drosophila melanogaster
PMAP Lima, PC Orsonlin, NM Machado… - … and Molecular Biology, 2024 - SciELO Brasil
Chemotherapy stands out as the main systemic treatment strategy against cancer and still
faces problems related to multidrug resistance and severe side effects. Copper-based drugs …
faces problems related to multidrug resistance and severe side effects. Copper-based drugs …
铜离子激活MAPK-ERK 通路调控鼻咽癌放射敏感性.
黄秀婷, 林颉, 叶晓心, 蔡佳佐… - Journal of Practical …, 2024 - search.ebscohost.com
目的探究铜离子(Cu2+) 对鼻咽癌(nasopharyngeal carcinoma, NPC) 细胞放射敏感性的影响,
寻找提升NPC 放疗效果的潜在靶标. 方法细胞Cu2+ 检测对比正常鼻咽上皮细胞系NP69 …
寻找提升NPC 放疗效果的潜在靶标. 方法细胞Cu2+ 检测对比正常鼻咽上皮细胞系NP69 …
铜螯合剂的作用: 神经科学的旧应用与新视角
R Leuci, L Brunetti, V Tufarelli, M Cerini… - 中国神经再生研究 …, 2025 - sjzsyj.com.cn
The role of copper element has been an increasingly relevant topic in recent years in the
fields of human and animal health, for both the study of new drugs and innovative food and …
fields of human and animal health, for both the study of new drugs and innovative food and …