We and others have previously shown that heat‐shock proteins (HSPs) are involved in
protecting the brain from a variety of insults including stroke, epilepsy, and other related …

Heat shock proteins (HSPs) are molecular chaperones involved in a variety of life activities.
HSPs function in the refolding of misfolded proteins, thereby contributing to the maintenance …

Hsp70s are highly conserved ATPase molecular chaperones mediating the correct folding of
de novo synthesized proteins, the translocation of proteins across membranes, the …

Infection with SARS-CoV-2 causes the coronavirus infectious disease 2019 (COVID-19), a
pandemic that has, at present, infected more than 11 million people globally. Some COVID …

Good health, which reflects the harmonious integration of molecules, cells, tissues and
organs, is dynamically stable: when displaced by disease, compensation and correction are …

Objective: Heat shock protein (HSP) expression is vital to cellular and tissue protection after
stress or injury. However, application of this powerful tool in human disease has been …

Hsp70s are conserved molecular chaperones that can prevent protein aggregation, actively
unfold, solubilize aggregates, pull translocating proteins across membranes and remodel …

Although heat shock proteins have been studied for decades, new intracellular and
extracellular functions in a variety of diseases continue to be discovered. Heat shock …

Heat shock proteins (HSPs) are chaperones that catalyze the refolding of denatured
proteins. In addition to their ability to prevent protein denaturation and aggregation, the …

Soluble 60 kDa heat shock protein (HSP60) activates macrophages via TLR4. We now
report that soluble HSP60 activates T cells via the innate receptor TLR2. HSP60 activated T …