In the past years, network theory has successfully characterized the interaction among the
constituents of a variety of complex systems, ranging from biological to technological, and …

The prediction of cellular function from a genotype is a fundamental goal in biology. For
metabolism, constraint-based modelling methods systematize biochemical, genetic and …

Multilayer networks is a rising topic in Network Science which characterizes the structure
and the function of complex systems formed by several interacting networks. Multilayer …

Most networked systems of scientific interest are characterized by temporal links, meaning
the network's structure changes over time. Link temporality has been shown to hinder many …

Despite considerable progress in genome-and proteome-based high-throughput screening
methods and in rational drug design, the increase in approved drugs in the past decade did …

Twitter, a microblogging service less than three years old, commands more than 41 million
users as of July 2009 and is growing fast. Twitter users tweet about any topic within the 140 …

Over the past decade, a growing community of researchers has emerged around the use of
constraint-based reconstruction and analysis (COBRA) methods to simulate, analyze and …

Reconstructed microbial metabolic networks facilitate a mechanistic description of the
genotype–phenotype relationship through the deployment of constraint-based …

Network reconstructions are a common denominator in systems biology. Bottom–up
metabolic network reconstructions have been developed over the last 10 years. These …

The availability of large data sets has allowed researchers to uncover complex properties
such as large-scale fluctuations and heterogeneities in many networks, leading to the …