Cisplatin is one of the most widely used chemotherapeutic agents for various solid tumors in
the clinic due to its high efficacy and broad spectrum. The antineoplastic activity of cisplatin …

Cisplatin is an antitumor drug used in the treatment of a wide variety of malignancies.
However, its primary dose‐limiting side effect is kidney injury, which is a major clinical …

Cisplatin is currently one of the most widely-used chemotherapeutic agents against various
malignancies. Its clinical application is limited, however, by inherent renal and cardiac …

Cisplatin is among the most effective chemotherapeutic agents against solid tumors.
Nephrotoxicity is the most common side effect of cisplatin chemotherapy, which limits the …

Platinum-based anticancer drugs (PADs), mainly cisplatin, carboplatin, and oxaliplatin, are
widely used efficacious long-standing anticancer agents for treating several cancer types …

Cisplatin is commonly used against several solid tumors, and oxaliplatin is an effective
cytotoxic drug used in colorectal cancer. A major clinical issue affecting 10–40% of patients …

This study aimed to assess the protective effect of hesperidin (HES) and rutin (RUT) against
cisplatin‐induced nephrotoxicity in male rats. Cisplatin (5 mg/kg, intraperitoneal) caused …

BACKGROUND: The anticancerdrug cisplatin (CP) causes nephrotoxicity through different
mechanisms, including generation of free radicals. Ellagic acid (EA) is a polyphenolic …

Cisplatin (cis-diaminedichloroplatinum II; CDDP) is an effective anticancer drug, but it has
limitations because of its nephrotoxicity. This study investigates the protective effect of N …

Cisplatin is one of the most widely used and effective chemotherapeutic agents for the
treatment of several human malignancies. This study evaluated the effects of peri‐pubertal …