[HTML][HTML] The infectious complications of atopic dermatitis

V Wang, J Boguniewicz, M Boguniewicz… - Annals of Allergy, Asthma …, 2021 - Elsevier
Objective Atopic dermatitis (AD) is a chronic inflammatory skin disease that is complicated
by an increased risk for skin and systemic infections. Preventive therapy for AD is based on …

IL-25 (IL-17E) in epithelial immunology and pathophysiology

J Borowczyk, M Shutova, NC Brembilla… - Journal of Allergy and …, 2021 - Elsevier
IL-25, also known as IL-17E, is a unique cytokine of the IL-17 family. Indeed, IL-25
exclusively was shown to strongly induce expression of the cytokines associated with type 2 …

Keratinocytes: innate immune cells in atopic dermatitis

P Chieosilapatham, C Kiatsurayanon… - Clinical & …, 2021 - academic.oup.com
The skin is a unique immune organ that constitutes a complex network of physical, chemical
and microbiological barriers against external insults. Keratinocytes are the most abundant …

[HTML][HTML] Th2 modulation of transient receptor potential channels: an unmet therapeutic intervention for atopic dermatitis

J Meng, Y Li, MJM Fischer, M Steinhoff… - Frontiers in …, 2021 - frontiersin.org
Atopic dermatitis (AD) is a multifaceted, chronic relapsing inflammatory skin disease that
affects people of all ages. It is characterized by chronic eczema, constant pruritus, and …

[HTML][HTML] Current insights into immunology and novel therapeutics of atopic dermatitis

HA Kader, M Azeem, SA Jwayed, A Al-Shehhi… - Cells, 2021 - mdpi.com
Atopic dermatitis (AD) is one of the most prevalent inflammatory disease among non-fatal
skin diseases, affecting up to one fifth of the population in developed countries. AD is …

[HTML][HTML] Cytokine-mediated crosstalk between keratinocytes and T cells in atopic dermatitis

M Humeau, K Boniface, C Bodet - Frontiers in immunology, 2022 - frontiersin.org
Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by barrier
dysfunction, dysregulated immune response, and dysbiosis with increased Staphylococcus …

Roles of innate lymphoid cells (ILCs) in allergic diseases: The 10-year anniversary for ILC2s

KR Bartemes, H Kita - Journal of Allergy and Clinical Immunology, 2021 - Elsevier
In the 12 years since the discovery of innate lymphoid cells (ILCs), our knowledge of their
immunobiology has expanded rapidly. Group 2 ILCs (ILC2s) respond rapidly to allergen …

Advances in atopic dermatitis in 2019-2020: Endotypes from skin barrier, ethnicity, properties of antigen, cytokine profiles, microbiome, and engagement of immune …

T Nomura, K Kabashima - Journal of Allergy and Clinical Immunology, 2021 - Elsevier
Key research advances in atopic dermatitis (AD) suggest the complexity of its endotypes. A
comprehensive serum biomarker panel revealed at least 4 types of AD. Some represent …

TSLP, IL-33, and IL-25: Not just for allergy and helminth infection

AG Stanbery, S Smita, J von Moltke, EDT Wojno… - Journal of Allergy and …, 2022 - Elsevier
The release of cytokines from epithelial and stromal cells is critical for the initiation and
maintenance of tissue immunity. Three such cytokines, thymic stromal lymphopoietin, IL-33 …

The impact of type 2 immunity and allergic diseases in atherosclerosis

N Fernández‐Gallego, R Castillo‐González… - Allergy, 2022 - Wiley Online Library
Allergic diseases are allergen‐induced immunological disorders characterized by the
development of type 2 immunity and IgE responses. The prevalence of allergic diseases has …